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Advanced Resistance Studies Identify Two Discrete Mechanisms in Staphylococcus aureus to Overcome Antibacterial Compounds that Target Biotin Protein Ligase.
Hayes AJ, Satiaputra J, Sternicki LM, Paparella AS, Feng Z, Lee KJ, Rodriguez BB, Tieu W, Eijkelkamp BA, Shearwin KE, Pukala TL, Abell AD, Booker GW, Polyak SW. Hayes AJ, et al. Among authors: lee kj. Antibiotics (Basel). 2020 Apr 6;9(4):165. doi: 10.3390/antibiotics9040165. Antibiotics (Basel). 2020. PMID: 32268615 Free PMC article.
Sulfonamide-Based Inhibitors of Biotin Protein Ligase as New Antibiotic Leads.
Lee KJ, Tieu W, Blanco-Rodriguez B, Paparella AS, Yu J, Hayes A, Feng J, Marshall AC, Noll B, Milne R, Cini D, Wilce MCJ, Booker GW, Bruning JB, Polyak SW, Abell AD. Lee KJ, et al. ACS Chem Biol. 2019 Sep 20;14(9):1990-1997. doi: 10.1021/acschembio.9b00463. Epub 2019 Aug 21. ACS Chem Biol. 2019. PMID: 31407891
Fortuitous In Vitro Compound Degradation Produces a Tractable Hit against Mycobacterium tuberculosis Dethiobiotin Synthetase: A Cautionary Tale of What Goes In Does Not Always Come Out.
Salaemae W, Thompson AP, Gaiser BI, Lee KJ, Huxley MT, Sumby CJ, Polyak SW, Abell AD, Bruning JB, Wegener KL. Salaemae W, et al. Among authors: lee kj. ACS Chem Biol. 2023 Sep 15;18(9):1985-1992. doi: 10.1021/acschembio.3c00215. Epub 2023 Aug 31. ACS Chem Biol. 2023. PMID: 37651626
3,609 results