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The dialkyl resorcinol stemphol disrupts calcium homeostasis to trigger programmed immunogenic necrosis in cancer.
Ji S, Lee JY, Schrör J, Mazumder A, Jang DM, Chateauvieux S, Schnekenburger M, Hong CR, Christov C, Kang HJ, Lee Y, Han BW, Kim KW, Shin HY, Dicato M, Cerella C, König GM, Orlikova B, Diederich M. Ji S, et al. Among authors: lee y, lee jy. Cancer Lett. 2018 Mar 1;416:109-123. doi: 10.1016/j.canlet.2017.12.011. Epub 2017 Dec 13. Cancer Lett. 2018. PMID: 29246646
Hydroxycoumarin OT-55 kills CML cells alone or in synergy with imatinib or Synribo: Involvement of ER stress and DAMP release.
Mazumder A, Lee JY, Talhi O, Cerella C, Chateauvieux S, Gaigneaux A, Hong CR, Kang HJ, Lee Y, Kim KW, Kim DW, Shin HY, Dicato M, Bachari K, Silva AMS, Orlikova-Boyer B, Diederich M. Mazumder A, et al. Among authors: lee y, lee jy. Cancer Lett. 2018 Dec 1;438:197-218. doi: 10.1016/j.canlet.2018.07.041. Epub 2018 Sep 8. Cancer Lett. 2018. PMID: 30205168
Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells.
Florean C, Schnekenburger M, Lee JY, Kim KR, Mazumder A, Song S, Kim JM, Grandjenette C, Kim JG, Yoon AY, Dicato M, Kim KW, Christov C, Han BW, Proksch P, Diederich M. Florean C, et al. Among authors: lee jy. Oncotarget. 2016 Apr 26;7(17):24027-49. doi: 10.18632/oncotarget.8210. Oncotarget. 2016. PMID: 27006469 Free PMC article.
Discovery and Characterization of R/S-N-3-Cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines.
Schnekenburger M, Goffin E, Lee JY, Jang JY, Mazumder A, Ji S, Rogister B, Bouider N, Lefranc F, Miklos W, Mathieu V, de Tullio P, Kim KW, Dicato M, Berger W, Han BW, Kiss R, Pirotte B, Diederich M. Schnekenburger M, et al. Among authors: lee jy. J Med Chem. 2017 Jun 8;60(11):4714-4733. doi: 10.1021/acs.jmedchem.7b00533. Epub 2017 May 25. J Med Chem. 2017. PMID: 28475330 Free article.
Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death.
Schneider NFZ, Cerella C, Lee JY, Mazumder A, Kim KR, de Carvalho A, Munkert J, Pádua RM, Kreis W, Kim KW, Christov C, Dicato M, Kim HJ, Han BW, Braga FC, Simões CMO, Diederich M. Schneider NFZ, et al. Among authors: lee jy. Front Pharmacol. 2018 Mar 1;9:70. doi: 10.3389/fphar.2018.00070. eCollection 2018. Front Pharmacol. 2018. PMID: 29545747 Free PMC article.
Tetrahydrobenzimidazole TMQ0153 triggers apoptosis, autophagy and necroptosis crosstalk in chronic myeloid leukemia.
Song S, Lee JY, Ermolenko L, Mazumder A, Ji S, Ryu H, Kim H, Kim DW, Lee JW, Dicato M, Christov C, Schnekenburger M, Cerella C, Gérard D, Orlikova-Boyer B, Al-Mourabit A, Diederich M. Song S, et al. Among authors: lee jw, lee jy. Cell Death Dis. 2020 Feb 7;11(2):109. doi: 10.1038/s41419-020-2304-8. Cell Death Dis. 2020. PMID: 32034134 Free PMC article.
Novel HDAC inhibitor MAKV-8 and imatinib synergistically kill chronic myeloid leukemia cells via inhibition of BCR-ABL/MYC-signaling: effect on imatinib resistance and stem cells.
Lernoux M, Schnekenburger M, Losson H, Vermeulen K, Hahn H, Gérard D, Lee JY, Mazumder A, Ahamed M, Christov C, Kim DW, Dicato M, Bormans G, Han BW, Diederich M. Lernoux M, et al. Among authors: lee jy. Clin Epigenetics. 2020 May 19;12(1):69. doi: 10.1186/s13148-020-00839-z. Clin Epigenetics. 2020. PMID: 32430012 Free PMC article.
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