Lee JY - Search Results

1

DynOmics: dynamics of structural proteome and beyond.

Li H, Chang YY, Lee JY, Bahar I, Yang LW. Li H, et al. Among authors: lee jy. Nucleic Acids Res. 2017 Jul 3;45(W1):W374-W380. doi: 10.1093/nar/gkx385. Nucleic Acids Res. 2017. PMID: 28472330 Free PMC article.

2

Structure-Encoded Global Motions and Their Role in Mediating Protein-Substrate Interactions.

Bahar I, Cheng MH, Lee JY, Kaya C, Zhang S. Bahar I, et al. Among authors: lee jy. Biophys J. 2015 Sep 15;109(6):1101-9. doi: 10.1016/j.bpj.2015.06.004. Epub 2015 Jul 2. Biophys J. 2015. PMID: 26143655 Free PMC article. Review.

3

Cooperative Dynamics of Intact AMPA and NMDA Glutamate Receptors: Similarities and Subfamily-Specific Differences.

Dutta A, Krieger J, Lee JY, Garcia-Nafria J, Greger IH, Bahar I. Dutta A, et al. Among authors: lee jy. Structure. 2015 Sep 1;23(9):1692-1704. doi: 10.1016/j.str.2015.07.002. Epub 2015 Aug 6. Structure. 2015. PMID: 26256538 Free PMC article.

4

Allosteric Modulation of Intact γ-Secretase Structural Dynamics.

Lee JY, Feng Z, Xie XQ, Bahar I. Lee JY, et al. Biophys J. 2017 Dec 19;113(12):2634-2649. doi: 10.1016/j.bpj.2017.10.012. Biophys J. 2017. PMID: 29262358 Free PMC article.

5

Activation and desensitization of ionotropic glutamate receptors by selectively triggering pre-existing motions.

Krieger J, Lee JY, Greger IH, Bahar I. Krieger J, et al. Among authors: lee jy. Neurosci Lett. 2019 May 1;700:22-29. doi: 10.1016/j.neulet.2018.02.050. Epub 2018 Feb 23. Neurosci Lett. 2019. PMID: 29481851 Free PMC article. Review.

6

Druggability Simulations and X-Ray Crystallography Reveal a Ligand-Binding Site in the GluA3 AMPA Receptor N-Terminal Domain.

Lee JY, Krieger J, Herguedas B, García-Nafría J, Dutta A, Shaikh SA, Greger IH, Bahar I. Lee JY, et al. Structure. 2019 Feb 5;27(2):241-252.e3. doi: 10.1016/j.str.2018.10.017. Epub 2018 Dec 6. Structure. 2019. PMID: 30528594 Free PMC article.

7

Trimerization of dopamine transporter triggered by AIM-100 binding: Molecular mechanism and effect of mutations.

Cheng MH, Ponzoni L, Sorkina T, Lee JY, Zhang S, Sorkin A, Bahar I. Cheng MH, et al. Among authors: lee jy. Neuropharmacology. 2019 Dec 15;161:107676. doi: 10.1016/j.neuropharm.2019.107676. Epub 2019 Jun 20. Neuropharmacology. 2019. PMID: 31228486 Free PMC article.

8

Pharmmaker: Pharmacophore modeling and hit identification based on druggability simulations.

Lee JY, Krieger JM, Li H, Bahar I. Lee JY, et al. Protein Sci. 2020 Jan;29(1):76-86. doi: 10.1002/pro.3732. Epub 2019 Dec 4. Protein Sci. 2020. PMID: 31576621 Free PMC article.

9

Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation.

Clark LJ, Krieger J, White AD, Bondarenko V, Lei S, Fang F, Lee JY, Doruker P, Böttke T, Jean-Alphonse F, Tang P, Gardella TJ, Xiao K, Sutkeviciute I, Coin I, Bahar I, Vilardaga JP. Clark LJ, et al. Among authors: lee jy. Nat Chem Biol. 2020 Oct;16(10):1096-1104. doi: 10.1038/s41589-020-0567-0. Epub 2020 Jul 6. Nat Chem Biol. 2020. PMID: 32632293 Free PMC article.

10

Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation.

White AD, Peña KA, Clark LJ, Maria CS, Liu S, Jean-Alphonse FG, Lee JY, Lei S, Cheng Z, Tu CL, Fang F, Szeto N, Gardella TJ, Xiao K, Gellman SH, Bahar I, Sutkeviciute I, Chang W, Vilardaga JP. White AD, et al. Among authors: lee jy. Sci Signal. 2021 Oct 5;14(703):eabc5944. doi: 10.1126/scisignal.abc5944. Epub 2021 Oct 5. Sci Signal. 2021. PMID: 34609896 Free PMC article.

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