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Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis.
Liu M, Cao S, He L, Gao J, Arab JP, Cui H, Xuan W, Gao Y, Sehrawat TS, Hamdan FH, Ventura-Cots M, Argemi J, Pomerantz WCK, Johnsen SA, Lee JH, Gao F, Ordog T, Mathurin P, Revzin A, Bataller R, Yan H, Shah VH. Liu M, et al. Among authors: lee jh. Nat Commun. 2021 Jul 27;12(1):4560. doi: 10.1038/s41467-021-24843-w. Nat Commun. 2021. PMID: 34315876 Free PMC article.
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas.
Fang D, Gan H, Lee JH, Han J, Wang Z, Riester SM, Jin L, Chen J, Zhou H, Wang J, Zhang H, Yang N, Bradley EW, Ho TH, Rubin BP, Bridge JA, Thibodeau SN, Ordog T, Chen Y, van Wijnen AJ, Oliveira AM, Xu RM, Westendorf JJ, Zhang Z. Fang D, et al. Among authors: lee jh. Science. 2016 Jun 10;352(6291):1344-8. doi: 10.1126/science.aae0065. Epub 2016 May 26. Science. 2016. PMID: 27229140 Free PMC article.
BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer.
Yokoyama Y, Zhu H, Lee JH, Kossenkov AV, Wu SY, Wickramasinghe JM, Yin X, Palozola KC, Gardini A, Showe LC, Zaret KS, Liu Q, Speicher D, Conejo-Garcia JR, Bradner JE, Zhang Z, Sood AK, Ordog T, Bitler BG, Zhang R. Yokoyama Y, et al. Among authors: lee jh. Cancer Res. 2016 Nov 1;76(21):6320-6330. doi: 10.1158/0008-5472.CAN-16-0854. Cancer Res. 2016. PMID: 27803105 Free PMC article.
CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity.
Karakashev S, Zhu H, Wu S, Yokoyama Y, Bitler BG, Park PH, Lee JH, Kossenkov AV, Gaonkar KS, Yan H, Drapkin R, Conejo-Garcia JR, Speicher DW, Ordog T, Zhang R. Karakashev S, et al. Among authors: lee jh. Nat Commun. 2018 Feb 12;9(1):631. doi: 10.1038/s41467-018-03031-3. Nat Commun. 2018. PMID: 29434212 Free PMC article.
Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes.
Lomberk G, Blum Y, Nicolle R, Nair A, Gaonkar KS, Marisa L, Mathison A, Sun Z, Yan H, Elarouci N, Armenoult L, Ayadi M, Ordog T, Lee JH, Oliver G, Klee E, Moutardier V, Gayet O, Bian B, Duconseil P, Gilabert M, Bigonnet M, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Secq V, De Reyniès A, Dusetti N, Iovanna J, Urrutia R. Lomberk G, et al. Among authors: lee jh. Nat Commun. 2018 May 17;9(1):1978. doi: 10.1038/s41467-018-04383-6. Nat Commun. 2018. PMID: 29773832 Free PMC article.
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