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Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression.
Sanidas I, Lee H, Rumde PH, Boulay G, Morris R, Golczer G, Stanzione M, Hajizadeh S, Zhong J, Ryan MB, Corcoran RB, Drapkin BJ, Rivera MN, Dyson NJ, Lawrence MS. Sanidas I, et al. Among authors: lee h. Mol Cell. 2022 Sep 15;82(18):3333-3349.e9. doi: 10.1016/j.molcel.2022.07.014. Epub 2022 Aug 17. Mol Cell. 2022. PMID: 35981542 Free PMC article.
Active RB causes visible changes in nuclear organization.
Krishnan B, Yasuhara T, Rumde P, Stanzione M, Lu C, Lee H, Lawrence MS, Zou L, Nieman LT, Sanidas I, Dyson NJ. Krishnan B, et al. Among authors: lee h. J Cell Biol. 2022 Mar 7;221(3):e202102144. doi: 10.1083/jcb.202102144. Epub 2022 Jan 12. J Cell Biol. 2022. PMID: 35019938 Free PMC article.
Revisiting the use of structural similarity index in Hi-C.
Lee H, Blumberg B, Lawrence MS, Shioda T. Lee H, et al. Nat Genet. 2023 Dec;55(12):2049-2052. doi: 10.1038/s41588-023-01594-6. Epub 2023 Dec 5. Nat Genet. 2023. PMID: 38052962 No abstract available.
Inhibition of de novo ceramide synthesis by Sirtuin-1 improves beta-cell function and glucose metabolism in type 2 diabetes.
Velagapudi S, Karsai G, Karsai M, Mohammed SA, Montecucco F, Liberale L, Lee H, Carbone F, Francesco Adami G, Yang K, Crucet M, Stein S, Paneni F, Lapikova-Bryhinska T, Jang HD, Kraler S, Vdovenko D, Arnold Züllig R, Camici GG, Kim HS, Laaksonen R, Gerber PA, Hornemann T, Akhmedov A, Lüscher TF. Velagapudi S, et al. Among authors: lee h. Cardiovasc Res. 2024 May 13:cvae100. doi: 10.1093/cvr/cvae100. Online ahead of print. Cardiovasc Res. 2024. PMID: 38739545
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