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Secreted Akkermansia muciniphila threonyl-tRNA synthetase functions to monitor and modulate immune homeostasis.
Kim SM, Park S, Hwang SH, Lee EY, Kim JH, Lee GS, Lee G, Chang DH, Lee JG, Hwang J, Lee Y, Kyung M, Kim EK, Kim JH, Kim TH, Moon JH, Kim BC, Ko G, Kim SY, Ryu JH, Lee JS, Lee CH, Kim JY, Kim S, Lee WJ, Kim MH. Kim SM, et al. Among authors: lee ch, lee ey, lee g, lee y, lee js, lee jg, lee gs, lee wj. Cell Host Microbe. 2023 Jun 14;31(6):1021-1037.e10. doi: 10.1016/j.chom.2023.05.007. Epub 2023 Jun 2. Cell Host Microbe. 2023. PMID: 37269833 Free article.
Structure-activity relationship analysis of novel GSPT1 degraders based on benzotriazinone scaffold and its antitumor effect on xenograft mouse model.
Takwale AD, Kim EY, Jang Y, Lee DH, Kim S, Choi Y, Kim JH, Lee DY, Kim Y, Lee SM, Lee HK, Nam HJ, Lee JY, Cho JH, Moon JH, Lee GS, Kim JH, Kim P, Park CH, Hwang JY. Takwale AD, et al. Bioorg Chem. 2022 Oct;127:105923. doi: 10.1016/j.bioorg.2022.105923. Epub 2022 Jun 13. Bioorg Chem. 2022. PMID: 35717803 Free article.
Discovery of pan-IAP degraders via a CRBN recruiting mechanism.
Park S, Kim D, Lee W, Cho JH, Kim S, Lee GS, Moon JH, Kim JA, Ha JD, Kim JH, Kim HJ. Park S, et al. Eur J Med Chem. 2023 Jan 5;245(Pt 2):114910. doi: 10.1016/j.ejmech.2022.114910. Epub 2022 Nov 9. Eur J Med Chem. 2023. PMID: 36410083
Endothelial PTP4A1 mitigates vascular inflammation via USF1/A20 axis-mediated NF-κB inactivation.
Cho MJ, Lee DG, Lee JW, Hwang B, Yoon SJ, Lee SJ, Park YJ, Park SH, Lee HG, Kim YH, Lee CH, Lee J, Lee NK, Han TS, Cho HS, Moon JH, Lee GS, Bae KH, Hwang GS, Lee SH, Chung SJ, Shim S, Cho J, Oh GT, Kwon YG, Park JG, Min JK. Cho MJ, et al. Cardiovasc Res. 2023 May 22;119(5):1265-1278. doi: 10.1093/cvr/cvac193. Cardiovasc Res. 2023. PMID: 36534975 Free PMC article.
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