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Rosiglitazone-dependent dissociation of HuR from PPAR-γ regulates adiponectin expression at the posttranscriptional level.
Hwang JS, Lee WJ, Hur J, Lee HG, Kim E, Lee GH, Choi MJ, Lim DS, Paek KS, Seo HG. Hwang JS, et al. FASEB J. 2019 Jun;33(6):7707-7720. doi: 10.1096/fj.201802643R. Epub 2019 Mar 21. FASEB J. 2019. PMID: 30897345
Taken together, the findings demonstrate a novel mechanism for regulating adiponectin expression at the posttranscriptional level and suggest that ligand-mediated activation of PPAR-gamma to interfere with interaction of HuR could offer a therapeutic strategy for inflammation-ass …
Taken together, the findings demonstrate a novel mechanism for regulating adiponectin expression at the posttranscriptional level and sugges …
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