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CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy.
Fry TJ, Shah NN, Orentas RJ, Stetler-Stevenson M, Yuan CM, Ramakrishna S, Wolters P, Martin S, Delbrook C, Yates B, Shalabi H, Fountaine TJ, Shern JF, Majzner RG, Stroncek DF, Sabatino M, Feng Y, Dimitrov DS, Zhang L, Nguyen S, Qin H, Dropulic B, Lee DW, Mackall CL. Fry TJ, et al. Among authors: lee dw. Nat Med. 2018 Jan;24(1):20-28. doi: 10.1038/nm.4441. Epub 2017 Nov 20. Nat Med. 2018. PMID: 29155426 Free PMC article. Clinical Trial.
Immunotherapy targets in pediatric cancer.
Orentas RJ, Lee DW, Mackall C. Orentas RJ, et al. Among authors: lee dw. Front Oncol. 2012 Jan 30;2:3. doi: 10.3389/fonc.2012.00003. eCollection 2012. Front Oncol. 2012. PMID: 22645714 Free PMC article.
Simplified process for the production of anti-CD19-CAR-engineered T cells.
Tumaini B, Lee DW, Lin T, Castiello L, Stroncek DF, Mackall C, Wayne A, Sabatino M. Tumaini B, et al. Among authors: lee dw. Cytotherapy. 2013 Nov;15(11):1406-15. doi: 10.1016/j.jcyt.2013.06.003. Epub 2013 Aug 28. Cytotherapy. 2013. PMID: 23992830 Free PMC article.
T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial.
Lee DW, Kochenderfer JN, Stetler-Stevenson M, Cui YK, Delbrook C, Feldman SA, Fry TJ, Orentas R, Sabatino M, Shah NN, Steinberg SM, Stroncek D, Tschernia N, Yuan C, Zhang H, Zhang L, Rosenberg SA, Wayne AS, Mackall CL. Lee DW, et al. Lancet. 2015 Feb 7;385(9967):517-528. doi: 10.1016/S0140-6736(14)61403-3. Epub 2014 Oct 13. Lancet. 2015. PMID: 25319501 Free PMC article. Clinical Trial.
Paving the road ahead for CD19 CAR T-cell therapy.
Nellan A, Lee DW. Nellan A, et al. Among authors: lee dw. Curr Opin Hematol. 2015 Nov;22(6):516-20. doi: 10.1097/MOH.0000000000000182. Curr Opin Hematol. 2015. PMID: 26335422 Free PMC article. Review.
2,301 results