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Discovery of novel tetrahydroisoquinoline-containing pyrimidines as ALK inhibitors.
Achary R, Yun JI, Park CM, Mathi GR, Lee JY, Ha JD, Chae CH, Ahn S, Park CH, Lee CO, Hwang JY, Yun CS, Jung HJ, Cho SY, Kim HR, Kim P. Achary R, et al. Among authors: lee co, lee jy. Bioorg Med Chem. 2016 Jan 15;24(2):207-19. doi: 10.1016/j.bmc.2015.12.004. Epub 2015 Dec 7. Bioorg Med Chem. 2016. PMID: 26712094
A novel cereblon modulator for targeted protein degradation.
Kim SA, Go A, Jo SH, Park SJ, Jeon YU, Kim JE, Lee HK, Park CH, Lee CO, Park SG, Kim P, Park BC, Cho SY, Kim S, Ha JD, Kim JH, Hwang JY. Kim SA, et al. Among authors: lee co, lee hk. Eur J Med Chem. 2019 Mar 15;166:65-74. doi: 10.1016/j.ejmech.2019.01.023. Epub 2019 Jan 17. Eur J Med Chem. 2019. PMID: 30684871
Novel bis-ortho-alkoxy-para-piperazinesubstituted-2,4-dianilinopyrimidines (KRCA-0008) as potent and selective ALK inhibitors for anticancer treatment.
Park CH, Choe H, Jang IY, Kwon SY, Latif M, Lee HK, Lee HJ, Yang EH, Yun JI, Chae CH, Cho SY, Choi SU, Ha JD, Jung H, Kim HR, Kim P, Lee CO, Yun CS, Lee K. Park CH, et al. Among authors: lee k, lee co, lee hk, lee hj. Bioorg Med Chem Lett. 2013 Nov 15;23(22):6192-6. doi: 10.1016/j.bmcl.2013.08.090. Epub 2013 Sep 4. Bioorg Med Chem Lett. 2013. PMID: 24095090
Development of potent ALK inhibitor and its molecular inhibitory mechanism against NSCLC harboring EML4-ALK proteins.
Kang CH, Yun JI, Lee K, Lee CO, Lee HK, Yun CS, Hwang JY, Cho SY, Jung H, Kim P, Ha JD, Jeon JH, Choi SU, Jeong HG, Kim HR, Park CH. Kang CH, et al. Among authors: lee k, lee co, lee hk. Biochem Biophys Res Commun. 2015 Aug 28;464(3):762-7. doi: 10.1016/j.bbrc.2015.07.027. Epub 2015 Jul 10. Biochem Biophys Res Commun. 2015. PMID: 26168728
251 results