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Page 1
"MiR-7 controls cholesterol biosynthesis through posttranscriptional regulation of DHCR24 expression".
Frutos MF, Pardo-Marqués V, Torrecilla-Parra M, Rada P, Pérez-García A, Martín-Martín Y, de la Peña G, Gómez A, Toledano-Zaragoza A, Gómez-Coronado D, Casarejos MJ, Solís JM, Rotllan N, Pastor Ó, Ledesma MD, Valverde ÁM, Busto R, Ramírez CM. Frutos MF, et al. Among authors: ledesma md. Biochim Biophys Acta Gene Regul Mech. 2023 Jun;1866(2):194938. doi: 10.1016/j.bbagrm.2023.194938. Epub 2023 Apr 21. Biochim Biophys Acta Gene Regul Mech. 2023. PMID: 37086967
Ellagic acid and its metabolites urolithins A/B ameliorate most common disease phenotypes in cellular and mouse models for lysosomal storage disorders by enhancing extracellular vesicle secretion.
Soto-Huelin B, Babiy B, Pastor O, Díaz-García M, Toledano-Zaragoza A, Frutos MD, Espín JC, Tomás-Barberán FA, Busto R, Ledesma MD. Soto-Huelin B, et al. Among authors: ledesma md. Neurobiol Dis. 2023 Jun 15;182:106141. doi: 10.1016/j.nbd.2023.106141. Epub 2023 Apr 28. Neurobiol Dis. 2023. PMID: 37121555 Free article.
Neurons regulate the esterification of bioactive lipid mediators in the brain of acid sphingomyelinase deficient mice.
Taha AY, Gaudioso Á, Moran-Garrido M, Camunas-Alberca SM, Bachiller-Hernández J, Sáiz J, Ledesma MD, Barbas C. Taha AY, et al. Among authors: ledesma md. Prog Neuropsychopharmacol Biol Psychiatry. 2024 Feb 8;129:110896. doi: 10.1016/j.pnpbp.2023.110896. Epub 2023 Nov 11. Prog Neuropsychopharmacol Biol Psychiatry. 2024. PMID: 37956788 Free article.
Efficacy and safety clinical trial with efavirenz in patients diagnosed with adult Niemann-pick type C with cognitive impairment.
Gascón-Bayarri J, Simon PC, Llop R, Carnaval T, Ledesma MD, Rico I, Sánchez-Castañeda C, Campdelacreu-Fumadó J, Calvo-Malvar N, Cos M, de Lama E, Cortés-Romera M, Rodríguez-Bel L, Pérez-Sousa C, Cerdán Sánchez M, Muelas N, Sevillano MD, Mir P, López de Munain A, Ferrer A, Videla S. Gascón-Bayarri J, et al. Among authors: ledesma md. Medicine (Baltimore). 2022 Dec 2;101(48):e31471. doi: 10.1097/MD.0000000000031471. Medicine (Baltimore). 2022. PMID: 36482560 Free PMC article.
Adult alcohol drinking and emotional tone are mediated by neutral sphingomyelinase during development in males.
Kalinichenko LS, Mühle C, Jia T, Anderheiden F, Datz M, Eberle AL, Eulenburg V, Granzow J, Hofer M, Hohenschild J, Huber SE, Kämpf S, Kogias G, Lacatusu L, Lugmair C, Taku SM, Meixner D, Sembritzki NK, Praetner M, Rhein C, Sauer C, Scholz J, Ulrich F, Valenta F, Weigand E, Werner M, Tay N, Mc Veigh CJ, Haase J, Wang AL, Abdel-Hafiz L, Huston JP, Smaga I, Frankowska M, Filip M, Lourdusamy A, Kirchner P, Ekici AB, Marx LM, Suresh NP, Frischknecht R, Fejtova A, Saied EM, Arenz C, Bozec A, Wank I, Kreitz S, Hess A, Bäuerle T, Ledesma MD, Mitroi DN, Miranda AM, Oliveira TG, Lenz B, Schumann G, Kornhuber J, Müller CP. Kalinichenko LS, et al. Among authors: ledesma md. Cereb Cortex. 2023 Jan 5;33(3):844-864. doi: 10.1093/cercor/bhac106. Cereb Cortex. 2023. PMID: 35296883
Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects.
Kalinichenko LS, Mühle C, Jia T, Anderheiden F, Datz M, Eberle AL, Eulenburg V, Granzow J, Hofer M, Hohenschild J, Huber SE, Kämpf S, Kogias G, Lacatusu L, Lugmair C, Taku SM, Meixner D, Tesch N, Praetner M, Rhein C, Sauer C, Scholz J, Ulrich F, Valenta F, Weigand E, Werner M, Tay N, Mc Veigh CJ, Haase J, Wang AL, Abdel-Hafiz L, Huston JP, Smaga I, Frankowska M, Filip M, Lourdusamy A, Kirchner P, Ekici AB, Marx LM, Suresh NP, Frischknecht R, Fejtova A, Saied EM, Arenz C, Bozec A, Wank I, Kreitz S, Hess A, Bäuerle T, Ledesma MD, Mitroi DN, Miranda AM, Oliveira TG, Gulbins E, Lenz B, Schumann G, Kornhuber J, Müller CP. Kalinichenko LS, et al. Among authors: ledesma md. Mol Psychiatry. 2021 Dec;26(12):7403-7416. doi: 10.1038/s41380-021-01304-w. Epub 2021 Sep 28. Mol Psychiatry. 2021. PMID: 34584229 Free PMC article.
65 results