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Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner.
Lecoutre S, Oger F, Pourpe C, Butruille L, Marousez L, Dickes-Coopman A, Laborie C, Guinez C, Lesage J, Vieau D, Junien C, Eberlé D, Gabory A, Eeckhoute J, Breton C. Lecoutre S, et al. Mol Metab. 2017 May 31;6(8):922-930. doi: 10.1016/j.molmet.2017.05.010. eCollection 2017 Aug. Mol Metab. 2017. PMID: 28752055 Free PMC article.
Reduced PPARγ2 expression in adipose tissue of male rat offspring from obese dams is associated with epigenetic modifications.
Lecoutre S, Pourpe C, Butruille L, Marousez L, Laborie C, Guinez C, Lesage J, Vieau D, Eeckhoute J, Gabory A, Oger F, Eberlé D, Breton C. Lecoutre S, et al. FASEB J. 2018 May;32(5):2768-2778. doi: 10.1096/fj.201700997R. Epub 2018 Jan 8. FASEB J. 2018. PMID: 29295860
Consistent with the DOHaD hypothesis, retained epigenetic marks provide a mechanistic basis for the cellular memory linking maternal obesity to a predisposition for later adiposity.-Lecoutre, S., Pourpe, C., Butruille, L., Marousez, L., Laborie, C., Guinez, C., Lesa …
Consistent with the DOHaD hypothesis, retained epigenetic marks provide a mechanistic basis for the cellular memory linking maternal obesity …
Transforming Growth Factor-β3 Regulates Adipocyte Number in Subcutaneous White Adipose Tissue.
Petrus P, Mejhert N, Corrales P, Lecoutre S, Li Q, Maldonado E, Kulyté A, Lopez Y, Campbell M, Acosta JR, Laurencikiene J, Douagi I, Gao H, Martínez-Álvarez C, Hedén P, Spalding KL, Vidal-Puig A, Medina-Gomez G, Arner P, Rydén M. Petrus P, et al. Among authors: lecoutre s. Cell Rep. 2018 Oct 16;25(3):551-560.e5. doi: 10.1016/j.celrep.2018.09.069. Cell Rep. 2018. PMID: 30332637 Free article.
26 results