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TGFBI Production by Macrophages Contributes to an Immunosuppressive Microenvironment in Ovarian Cancer.
Lecker LSM, Berlato C, Maniati E, Delaine-Smith R, Pearce OMT, Heath O, Nichols SJ, Trevisan C, Novak M, McDermott J, Brenton JD, Cutillas PR, Rajeeve V, Hennino A, Drapkin R, Loessner D, Balkwill FR. Lecker LSM, et al. Cancer Res. 2021 Nov 15;81(22):5706-5719. doi: 10.1158/0008-5472.CAN-21-0536. Epub 2021 Sep 24. Cancer Res. 2021. PMID: 34561272 Free PMC article.
Large scale in vivo micro-RNA loss of function screen identified miR-29a, miR-100 and miR-155 as modulators of radioresistance and tumor-stroma communication.
Fahim Golestaneh A, Lecker LSM, Schlegel J, Nowrouzi A, Schwager C, Meister S, Weichert W, Debus J, Abdollahi A. Fahim Golestaneh A, et al. Among authors: lecker lsm. Int J Cancer. 2019 Jun 1;144(11):2774-2781. doi: 10.1002/ijc.32019. Epub 2019 Jan 4. Int J Cancer. 2019. PMID: 30478850 Free article.
A randomized clinical trial on the short-term effects of 12-week sacubitril/valsartan vs. enalapril on peak oxygen consumption in patients with heart failure with reduced ejection fraction: results from the ACTIVITY-HF study.
Halle M, Schöbel C, Winzer EB, Bernhardt P, Mueller S, Sieder C, Lecker LSM. Halle M, et al. Among authors: lecker lsm. Eur J Heart Fail. 2021 Dec;23(12):2073-2082. doi: 10.1002/ejhf.2355. Epub 2021 Oct 12. Eur J Heart Fail. 2021. PMID: 34591356 Free article. Clinical Trial.
Structures of Pseudomonas aeruginosa β-ketoacyl-(acyl-carrier-protein) synthase II (FabF) and a C164Q mutant provide templates for antibacterial drug discovery and identify a buried potassium ion and a ligand-binding site that is an artefact of the crystal form.
Baum B, Lecker LS, Zoltner M, Jaenicke E, Schnell R, Hunter WN, Brenk R. Baum B, et al. Acta Crystallogr F Struct Biol Commun. 2015 Aug;71(Pt 8):1020-6. doi: 10.1107/S2053230X15010614. Epub 2015 Jul 28. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 26249693 Free PMC article.