Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

30 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound.
Lara LS, Moreira CS, Calvet CM, Lechuga GC, Souza RS, Bourguignon SC, Ferreira VF, Rocha D, Pereira MCS. Lara LS, et al. Among authors: lechuga gc. Eur J Med Chem. 2018 Jan 20;144:572-581. doi: 10.1016/j.ejmech.2017.12.052. Epub 2017 Dec 16. Eur J Med Chem. 2018. PMID: 29289882
Heme crystallization in a Chagas disease vector acts as a redox-protective mechanism to allow insect reproduction and parasite infection.
Ferreira CM, Stiebler R, Saraiva FM, Lechuga GC, Walter-Nuno AB, Bourguignon SC, Gonzalez MS, Azambuja P, Gandara ACP, Menna-Barreto RFS, Paiva-Silva GO, Paes MC, Oliveira MF. Ferreira CM, et al. Among authors: lechuga gc. PLoS Negl Trop Dis. 2018 Jul 23;12(7):e0006661. doi: 10.1371/journal.pntd.0006661. eCollection 2018 Jul. PLoS Negl Trop Dis. 2018. PMID: 30036366 Free PMC article.
The combination therapy of meglumine antimoniate and oxiranes (epoxy-α-lapachone and epoxymethyl-lawsone) enhance the leishmanicidal effect in mice infected by Leishmania (Leishmania) amazonensis.
Gonçalves-Oliveira LF, Souza-Silva F, de Castro Côrtes LM, Veloso LB, Santini Pereira BA, Cysne-Finkelstein L, Lechuga GC, Bourguignon SC, Almeida-Souza F, da Silva Calabrese K, Ferreira VF, Alves CR. Gonçalves-Oliveira LF, et al. Among authors: lechuga gc. Int J Parasitol Drugs Drug Resist. 2019 Aug;10:101-108. doi: 10.1016/j.ijpddr.2019.08.002. Epub 2019 Aug 12. Int J Parasitol Drugs Drug Resist. 2019. PMID: 31430693 Free PMC article.
Synthesis, structure-activity relationship and trypanocidal activity of pyrazole-imidazoline and new pyrazole-tetrahydropyrimidine hybrids as promising chemotherapeutic agents for Chagas disease.
Monteiro ME, Lechuga G, Lara LS, Souto BA, Viganó MG, Bourguignon SC, Calvet CM, Oliveira FOR Jr, Alves CR, Souza-Silva F, Santos MS, Pereira MCS. Monteiro ME, et al. Eur J Med Chem. 2019 Nov 15;182:111610. doi: 10.1016/j.ejmech.2019.111610. Epub 2019 Aug 10. Eur J Med Chem. 2019. PMID: 31434040
Structural Optimization and Biological Activity of Pyrazole Derivatives: Virtual Computational Analysis, Recovery Assay and 3D Culture Model as Potential Predictive Tools of Effectiveness against Trypanosoma cruzi.
Orlando LMR, Lechuga GC, da Silva Lara L, Ferreira BS, Pereira CN, Silva RC, Dos Santos MS, Pereira MCS. Orlando LMR, et al. Among authors: lechuga gc. Molecules. 2021 Nov 8;26(21):6742. doi: 10.3390/molecules26216742. Molecules. 2021. PMID: 34771151 Free PMC article.
30 results