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Specific Activation of the Alternative Cardiac Promoter of Cacna1c by the Mineralocorticoid Receptor.
Mesquita TR, Auguste G, Falcón D, Ruiz-Hurtado G, Salazar-Enciso R, Sabourin J, Lefebvre F, Viengchareun S, Kobeissy H, Lechène P, Nicolas V, Fernandez-Celis A, Gómez S, Lauton Santos S, Morel E, Rueda A, López-Andrés N, Gómez AM, Lombès M, Benitah JP. Mesquita TR, et al. Among authors: lechene p. Circ Res. 2018 Mar 30;122(7):e49-e61. doi: 10.1161/CIRCRESAHA.117.312451. Epub 2018 Feb 21. Circ Res. 2018. PMID: 29467196
Cardiac Overexpression of PDE4B Blunts β-Adrenergic Response and Maladaptive Remodeling in Heart Failure.
Karam S, Margaria JP, Bourcier A, Mika D, Varin A, Bedioune I, Lindner M, Bouadjel K, Dessillons M, Gaudin F, Lefebvre F, Mateo P, Lechène P, Gomez S, Domergue V, Robert P, Coquard C, Algalarrondo V, Samuel JL, Michel JB, Charpentier F, Ghigo A, Hirsch E, Fischmeister R, Leroy J, Vandecasteele G. Karam S, et al. Among authors: lechene p. Circulation. 2020 Jul 14;142(2):161-174. doi: 10.1161/CIRCULATIONAHA.119.042573. Epub 2020 Apr 8. Circulation. 2020. PMID: 32264695
Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes.
Haj Slimane Z, Bedioune I, Lechêne P, Varin A, Lefebvre F, Mateo P, Domergue-Dupont V, Dewenter M, Richter W, Conti M, El-Armouche A, Zhang J, Fischmeister R, Vandecasteele G. Haj Slimane Z, et al. Among authors: lechene p. Cardiovasc Res. 2014 Apr 1;102(1):97-106. doi: 10.1093/cvr/cvu029. Epub 2014 Feb 18. Cardiovasc Res. 2014. PMID: 24550350 Free PMC article.
Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes.
Mehel H, Emons J, Vettel C, Wittköpper K, Seppelt D, Dewenter M, Lutz S, Sossalla S, Maier LS, Lechêne P, Leroy J, Lefebvre F, Varin A, Eschenhagen T, Nattel S, Dobrev D, Zimmermann WH, Nikolaev VO, Vandecasteele G, Fischmeister R, El-Armouche A. Mehel H, et al. Among authors: lechene p. J Am Coll Cardiol. 2013 Oct 22;62(17):1596-606. doi: 10.1016/j.jacc.2013.05.057. Epub 2013 Jun 26. J Am Coll Cardiol. 2013. PMID: 23810893 Free article.
Synergic PDE3 and PDE4 control intracellular cAMP and cardiac excitation-contraction coupling in a porcine model.
Mika D, Bobin P, Lindner M, Boet A, Hodzic A, Lefebvre F, Lechène P, Sadoune M, Samuel JL, Algalarrondo V, Rucker-Martin C, Lambert V, Fischmeister R, Vandecasteele G, Leroy J. Mika D, et al. Among authors: lechene p. J Mol Cell Cardiol. 2019 Aug;133:57-66. doi: 10.1016/j.yjmcc.2019.05.025. Epub 2019 May 31. J Mol Cell Cardiol. 2019. PMID: 31158360
Standard and Strain Measurements by Echocardiography Detect Early Overloaded Right Ventricular Dysfunction: Validation against Hemodynamic and Myocyte Contractility Changes in a Large Animal Model.
Hodzic A, Bobin P, Mika D, Ly M, Lefebvre F, Lechêne P, Le Bret E, Gouadon E, Coblence M, Vandecasteele G, Capderou A, Leroy J, Rucker-Martin C, Lambert V. Hodzic A, et al. Among authors: lechene p. J Am Soc Echocardiogr. 2017 Nov;30(11):1138-1147.e4. doi: 10.1016/j.echo.2017.07.003. Epub 2017 Aug 30. J Am Soc Echocardiogr. 2017. PMID: 28864150
Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction.
Vettel C, Lindner M, Dewenter M, Lorenz K, Schanbacher C, Riedel M, Lämmle S, Meinecke S, Mason FE, Sossalla S, Geerts A, Hoffmann M, Wunder F, Brunner FJ, Wieland T, Mehel H, Karam S, Lechêne P, Leroy J, Vandecasteele G, Wagner M, Fischmeister R, El-Armouche A. Vettel C, et al. Among authors: lechene p. Circ Res. 2017 Jan 6;120(1):120-132. doi: 10.1161/CIRCRESAHA.116.310069. Epub 2016 Oct 31. Circ Res. 2017. PMID: 27799254
37 results