Lebon F - Search Results

1

Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist.

Sun B, Feng D, Chu ML, Fish I, Lovera S, Sands ZA, Kelm S, Valade A, Wood M, Ceska T, Kobilka TS, Lebon F, Kobilka BK. Sun B, et al. Among authors: lebon f. Nat Commun. 2021 Jun 3;12(1):3305. doi: 10.1038/s41467-021-23519-9. Nat Commun. 2021. PMID: 34083522 Free PMC article.

2

Crystal structure of the adenosine A_2A receptor bound to an antagonist reveals a potential allosteric pocket.

Sun B, Bachhawat P, Chu ML, Wood M, Ceska T, Sands ZA, Mercier J, Lebon F, Kobilka TS, Kobilka BK. Sun B, et al. Among authors: lebon f. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):2066-2071. doi: 10.1073/pnas.1621423114. Epub 2017 Feb 6. Proc Natl Acad Sci U S A. 2017. PMID: 28167788 Free PMC article.

3

Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A.

Benoit RM, Frey D, Hilbert M, Kevenaar JT, Wieser MM, Stirnimann CU, McMillan D, Ceska T, Lebon F, Jaussi R, Steinmetz MO, Schertler GF, Hoogenraad CC, Capitani G, Kammerer RA. Benoit RM, et al. Among authors: lebon f. Nature. 2014 Jan 2;505(7481):108-11. doi: 10.1038/nature12732. Epub 2013 Nov 17. Nature. 2014. PMID: 24240280

4

Exploring the interaction of SV2A with racetams using homology modelling, molecular dynamics and site-directed mutagenesis.

Lee J, Daniels V, Sands ZA, Lebon F, Shi J, Biggin PC. Lee J, et al. Among authors: lebon f. PLoS One. 2015 Feb 18;10(2):e0116589. doi: 10.1371/journal.pone.0116589. eCollection 2015. PLoS One. 2015. PMID: 25692762 Free PMC article.

5

Arylsulfonamides as a new class of cannabinoid CB1 receptor ligands: identification of a lead and initial SAR studies.

Lambeng N, Lebon F, Christophe B, Burton M, De Ryck M, Quéré L. Lambeng N, et al. Among authors: lebon f. Bioorg Med Chem Lett. 2007 Jan 1;17(1):272-7. doi: 10.1016/j.bmcl.2006.09.049. Epub 2006 Oct 5. Bioorg Med Chem Lett. 2007. PMID: 17027269

6

Combining modelling and mutagenesis studies of synaptic vesicle protein 2A to identify a series of residues involved in racetam binding.

Shi J, Anderson D, Lynch BA, Castaigne JG, Foerch P, Lebon F. Shi J, et al. Among authors: lebon f. Biochem Soc Trans. 2011 Oct;39(5):1341-7. doi: 10.1042/BST0391341. Biochem Soc Trans. 2011. PMID: 21936812

7

First dual M3 antagonists-PDE4 inhibitors: synthesis and SAR of 4,6-diaminopyrimidine derivatives.

Provins L, Christophe B, Danhaive P, Dulieu J, Durieu V, Gillard M, Lebon F, Lengelé S, Quéré L, van Keulen B. Provins L, et al. Among authors: lebon f. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1834-9. doi: 10.1016/j.bmcl.2006.01.006. Epub 2006 Jan 24. Bioorg Med Chem Lett. 2006. PMID: 16439121

8

Discovery of a new class of non-imidazole oxazoline-based histamine H(3) receptor (H(3)R) inverse agonists.

Célanire S, Wijtmans M, Christophe B, Collart P, de Esch I, Dassesse D, Delaunoy C, Denonne F, Durieu V, Gelens E, Gillard M, Lallemand B, Lamberty Y, Lebon F, Nicolas JM, Quéré L, Snip E, Vanbellinghen A, Van Houtvin N, Verbois V, Timmerman H, Talaga P, Leurs R, Provins L. Célanire S, et al. Among authors: lebon f. ChemMedChem. 2009 Jul;4(7):1063-8. doi: 10.1002/cmdc.200900055. ChemMedChem. 2009. PMID: 19405064

9

4-benzyl-1H-imidazoles with oxazoline termini as histamine H3 receptor agonists.

Wijtmans M, Celanire S, Snip E, Gillard MR, Gelens E, Collart PP, Venhuis BJ, Christophe B, Hulscher S, van der Goot H, Lebon F, Timmerman H, Bakker RA, Lallemand BI, Leurs R, Talaga PE, de Esch IJ. Wijtmans M, et al. Among authors: lebon f. J Med Chem. 2008 May 22;51(10):2944-53. doi: 10.1021/jm7014149. Epub 2008 Apr 24. J Med Chem. 2008. PMID: 18433114

10

Towards a KCC2 blocker pharmacophore model.

Lebon F, Pégurier C, Ledecq M, Mathieu B, Bosman N, Frycia A, Lengelé S, Dhurke K, Kanduluru AK, Meunier S, Wagner A, Wolff C, Provins L. Lebon F, et al. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3978-82. doi: 10.1016/j.bmcl.2012.04.097. Epub 2012 Apr 30. Bioorg Med Chem Lett. 2012. PMID: 22608391

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