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A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma.
Haugaard-Kedström LM, Clemmensen LS, Sereikaite V, Jin Z, Fernandes EFA, Wind B, Abalde-Gil F, Daberger J, Vistrup-Parry M, Aguilar-Morante D, Leblanc R, Egea-Jimenez AL, Albrigtsen M, Jensen KE, Jensen TMT, Ivarsson Y, Vincentelli R, Hamerlik P, Andersen JH, Zimmermann P, Lee W, Strømgaard K. Haugaard-Kedström LM, et al. Among authors: leblanc r. J Med Chem. 2021 Feb 11;64(3):1423-1434. doi: 10.1021/acs.jmedchem.0c00382. Epub 2021 Jan 27. J Med Chem. 2021. PMID: 33502198
Tetraspanin-6 negatively regulates exosome production.
Ghossoub R, Chéry M, Audebert S, Leblanc R, Egea-Jimenez AL, Lembo F, Mammar S, Le Dez F, Camoin L, Borg JP, Rubinstein E, David G, Zimmermann P. Ghossoub R, et al. Among authors: leblanc r. Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):5913-5922. doi: 10.1073/pnas.1922447117. Epub 2020 Feb 27. Proc Natl Acad Sci U S A. 2020. PMID: 32108028 Free PMC article.
Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo.
Leblanc R, Kashyap R, Barral K, Egea-Jimenez AL, Kovalskyy D, Feracci M, Garcia M, Derviaux C, Betzi S, Ghossoub R, Platonov M, Roche P, Morelli X, Hoffer L, Zimmermann P. Leblanc R, et al. J Extracell Vesicles. 2020 Dec;10(2):e12039. doi: 10.1002/jev2.12039. Epub 2020 Dec 15. J Extracell Vesicles. 2020. PMID: 33343836 Free PMC article.
PDZ scaffolds regulate extracellular vesicle production, composition, and uptake.
Castro-Cruz M, Hyka L, Daaboul G, Leblanc R, Meeussen S, Lembo F, Oris A, Van Herck L, Granjeaud S, David G, Zimmermann P. Castro-Cruz M, et al. Among authors: leblanc r. Proc Natl Acad Sci U S A. 2023 Sep 19;120(38):e2310914120. doi: 10.1073/pnas.2310914120. Epub 2023 Sep 11. Proc Natl Acad Sci U S A. 2023. PMID: 37695903 Free PMC article.
Downregulation of stromal syntenin sustains AML development.
Leblanc R, Ghossoub R, Goubard A, Castellano R, Fares J, Camoin L, Audebert S, Balzano M, Bou-Tayeh B, Fauriat C, Vey N, Garciaz S, Borg JP, Collette Y, Aurrand-Lions M, David G, Zimmermann P. Leblanc R, et al. EMBO Mol Med. 2023 Nov 8;15(11):e17570. doi: 10.15252/emmm.202317570. Epub 2023 Oct 11. EMBO Mol Med. 2023. PMID: 37819151 Free PMC article.
823 results