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The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis.
Stoup N, Liberelle M, Schulz C, Cavdarli S, Vasseur R, Magnez R, Lahdaoui F, Skrypek N, Peretti F, Frénois F, Thuru X, Melnyk P, Renault N, Jonckheere N, Lebègue N, Van Seuningen I. Stoup N, et al. Among authors: lebegue n. Cancers (Basel). 2021 Nov 16;13(22):5746. doi: 10.3390/cancers13225746. Cancers (Basel). 2021. PMID: 34830899 Free PMC article.
MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis.
Liberelle M, Magnez R, Thuru X, Bencheikh Y, Ravez S, Quenon C, Drucbert AS, Foulon C, Melnyk P, Van Seuningen I, Lebègue N. Liberelle M, et al. Among authors: lebegue n. Sci Rep. 2019 Nov 13;9(1):16678. doi: 10.1038/s41598-019-53099-0. Sci Rep. 2019. PMID: 31723153 Free PMC article.
A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively.
Marchand A, Sarchione A, Athanasopoulos PS, Roy HB, Goveas L, Magnez R, Drouyer M, Emanuele M, Ho FY, Liberelle M, Melnyk P, Lebègue N, Thuru X, Nichols RJ, Greggio E, Kortholt A, Galli T, Chartier-Harlin MC, Taymans JM. Marchand A, et al. Among authors: lebegue n. Cells. 2022 Mar 17;11(6):1018. doi: 10.3390/cells11061018. Cells. 2022. PMID: 35326469 Free PMC article.
Synthesis and Biological Evaluation of N-[2-(4-Hydroxyphenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide (ABT-751) Tricyclic Analogues as Antimitotic and Antivascular Agents with Potent in Vivo Antitumor Activity.
Segaoula Z, Leclercq J, Verones V, Flouquet N, Lecoeur M, Ach L, Renault N, Barczyk A, Melnyk P, Berthelot P, Thuru X, Lebegue N. Segaoula Z, et al. Among authors: lebegue n. J Med Chem. 2016 Sep 22;59(18):8422-40. doi: 10.1021/acs.jmedchem.6b00847. Epub 2016 Aug 30. J Med Chem. 2016. PMID: 27538123 Free article.
Effect of 6-Benzoyl-benzothiazol-2-one scaffold on the pharmacological profile of α-alkoxyphenylpropionic acid derived PPAR agonists.
Hurtevent A, Le Naour M, Leclerc V, Carato P, Melnyk P, Hennuyer N, Staels B, Beucher-Gaudin M, Caignard DH, Dacquet C, Lebegue N. Hurtevent A, et al. Among authors: lebegue n. J Enzyme Inhib Med Chem. 2020 Dec;35(1):524-538. doi: 10.1080/14756366.2020.1713771. J Enzyme Inhib Med Chem. 2020. PMID: 31939313 Free PMC article.
29 results