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A new paradigm for leprosy diagnosis based on host gene expression.
Leal-Calvo T, Avanzi C, Mendes MA, Benjak A, Busso P, Pinheiro RO, Sarno EN, Cole ST, Moraes MO. Leal-Calvo T, et al. PLoS Pathog. 2021 Oct 25;17(10):e1009972. doi: 10.1371/journal.ppat.1009972. eCollection 2021 Oct. PLoS Pathog. 2021. PMID: 34695167 Free PMC article.
Gene expression patterns associated with multidrug therapy in multibacillary leprosy.
Ferreira H, Leal-Calvo T, Mendes MA, Avanzi C, Busso P, Benjak A, Sales AM, Ferreira CP, de Berrêdo-Pinho M, Cole ST, Sarno EN, Moraes MO, Pinheiro RO. Ferreira H, et al. Among authors: leal calvo t. Front Cell Infect Microbiol. 2022 Jul 22;12:917282. doi: 10.3389/fcimb.2022.917282. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35937686 Free PMC article.
Large-Scale Gene Expression Signatures Reveal a Microbicidal Pattern of Activation in Mycobacterium leprae-Infected Monocyte-Derived Macrophages With Low Multiplicity of Infection.
Leal-Calvo T, Martins BL, Bertoluci DF, Rosa PS, de Camargo RM, Germano GV, Brito de Souza VN, Pereira Latini AC, Moraes MO. Leal-Calvo T, et al. Front Immunol. 2021 Apr 16;12:647832. doi: 10.3389/fimmu.2021.647832. eCollection 2021. Front Immunol. 2021. PMID: 33936067 Free PMC article.
The Type I Interferon Pathway Is Upregulated in the Cutaneous Lesions and Blood of Multibacillary Leprosy Patients With Erythema Nodosum Leprosum.
Rosa TLSA, Mendes MA, Linhares NRC, Rodrigues TF, Dias AA, Leal-Calvo T, Gandini M, Ferreira H, Costa FDMR, Sales AM, Amadeu TP, Schmitz V, Pinheiro RO, Rodrigues LS, Moraes MO, Pessolani MCV. Rosa TLSA, et al. Among authors: leal calvo t. Front Med (Lausanne). 2022 Jun 6;9:899998. doi: 10.3389/fmed.2022.899998. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35733868 Free PMC article.
Development and validation of a multiplex real-time qPCR assay using GMP-grade reagents for leprosy diagnosis.
Manta FSN, Jacomasso T, Rampazzo RCP, Moreira SJM, Zahra NM, Cole ST, Avanzi C, Leal-Calvo T, Vasconcellos SEG, Suffys P, Ribeiro-Alves M, Krieger MA, Costa ADT, Moraes MO. Manta FSN, et al. Among authors: leal calvo t. PLoS Negl Trop Dis. 2022 Feb 18;16(2):e0009850. doi: 10.1371/journal.pntd.0009850. eCollection 2022 Feb. PLoS Negl Trop Dis. 2022. PMID: 35180224 Free PMC article.
Ultra-sensitive detection of Mycobacterium leprae: DNA extraction and PCR assays.
Manta FSN, Leal-Calvo T, Moreira SJM, Marques BLC, Ribeiro-Alves M, Rosa PS, Nery JAC, Rampazzo RCP, Costa ADT, Krieger MA, Moraes MO. Manta FSN, et al. PLoS Negl Trop Dis. 2020 May 26;14(5):e0008325. doi: 10.1371/journal.pntd.0008325. eCollection 2020 May. PLoS Negl Trop Dis. 2020. PMID: 32453754 Free PMC article.
Putative pathogen-selected polymorphisms in the PKLR gene are associated with mycobacterial susceptibility in Brazilian and African populations.
Bezerra OCL, Alvarado-Arnez LE, Mabunda N, Salomé G, de Sousa A, Kehdy FSG, Sales-Marques C, Manta FSN, Andrade RM, Ferreira LP, Leal-Calvo T, Cardoso CC, Nunes K, Gouveia MH, Mbulaiteve SM, Yeboah ED, Hsing A, Latini ACP, Leturiondo AL, Rodrigues FDC, Noronha AB, Ferreira CO, Talhari C, Rêgo JL, Castellucci LCC, Tarazona-Santos E, Carvalho EF, Meyer D, Pinheiro RO, Jani IV, Pacheco AG, Moraes MO. Bezerra OCL, et al. PLoS Negl Trop Dis. 2021 Aug 27;15(8):e0009434. doi: 10.1371/journal.pntd.0009434. eCollection 2021 Aug. PLoS Negl Trop Dis. 2021. PMID: 34449765 Free PMC article.
18 results