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Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.
Martin JC, Chang C, Boschetti G, Ungaro R, Giri M, Grout JA, Gettler K, Chuang LS, Nayar S, Greenstein AJ, Dubinsky M, Walker L, Leader A, Fine JS, Whitehurst CE, Mbow ML, Kugathasan S, Denson LA, Hyams JS, Friedman JR, Desai PT, Ko HM, Laface I, Akturk G, Schadt EE, Salmon H, Gnjatic S, Rahman AH, Merad M, Cho JH, Kenigsberg E. Martin JC, et al. Among authors: leader a. Cell. 2019 Sep 5;178(6):1493-1508.e20. doi: 10.1016/j.cell.2019.08.008. Epub 2019 Aug 29. Cell. 2019. PMID: 31474370 Free PMC article.
Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses.
Lavin Y, Kobayashi S, Leader A, Amir ED, Elefant N, Bigenwald C, Remark R, Sweeney R, Becker CD, Levine JH, Meinhof K, Chow A, Kim-Shulze S, Wolf A, Medaglia C, Li H, Rytlewski JA, Emerson RO, Solovyov A, Greenbaum BD, Sanders C, Vignali M, Beasley MB, Flores R, Gnjatic S, Pe'er D, Rahman A, Amit I, Merad M. Lavin Y, et al. Among authors: leader a. Cell. 2017 May 4;169(4):750-765.e17. doi: 10.1016/j.cell.2017.04.014. Cell. 2017. PMID: 28475900 Free PMC article.
CSF-1 controls cerebellar microglia and is required for motor function and social interaction.
Kana V, Desland FA, Casanova-Acebes M, Ayata P, Badimon A, Nabel E, Yamamuro K, Sneeboer M, Tan IL, Flanigan ME, Rose SA, Chang C, Leader A, Le Bourhis H, Sweet ES, Tung N, Wroblewska A, Lavin Y, See P, Baccarini A, Ginhoux F, Chitu V, Stanley ER, Russo SJ, Yue Z, Brown BD, Joyner AL, De Witte LD, Morishita H, Schaefer A, Merad M. Kana V, et al. Among authors: leader a. J Exp Med. 2019 Oct 7;216(10):2265-2281. doi: 10.1084/jem.20182037. Epub 2019 Jul 26. J Exp Med. 2019. PMID: 31350310 Free PMC article.
A conserved dendritic-cell regulatory program limits antitumour immunity.
Maier B, Leader AM, Chen ST, Tung N, Chang C, LeBerichel J, Chudnovskiy A, Maskey S, Walker L, Finnigan JP, Kirkling ME, Reizis B, Ghosh S, D'Amore NR, Bhardwaj N, Rothlin CV, Wolf A, Flores R, Marron T, Rahman AH, Kenigsberg E, Brown BD, Merad M. Maier B, et al. Among authors: leader am. Nature. 2020 Apr;580(7802):257-262. doi: 10.1038/s41586-020-2134-y. Epub 2020 Mar 25. Nature. 2020. PMID: 32269339 Free PMC article.
Advancing scientific knowledge in times of pandemics.
Vabret N, Samstein R, Fernandez N, Merad M; Sinai Immunology Review Project; Trainees; Faculty. Vabret N, et al. Nat Rev Immunol. 2020 Jun;20(6):338. doi: 10.1038/s41577-020-0319-0. Nat Rev Immunol. 2020. PMID: 32327718 Free PMC article.
Author Correction: A conserved dendritic-cell regulatory program limits antitumour immunity.
Maier B, Leader AM, Chen ST, Tung N, Chang C, LeBerichel J, Chudnovskiy A, Maskey S, Walker L, Finnigan JP, Kirkling ME, Reizis B, Ghosh S, D'Amore NR, Bhardwaj N, Rothlin CV, Wolf A, Flores R, Marron T, Rahman AH, Kenigsberg E, Brown BD, Merad M. Maier B, et al. Among authors: leader am. Nature. 2020 Jun;582(7813):E17. doi: 10.1038/s41586-020-2326-5. Nature. 2020. PMID: 32499658
Immunology of COVID-19: Current State of the Science.
Vabret N, Britton GJ, Gruber C, Hegde S, Kim J, Kuksin M, Levantovsky R, Malle L, Moreira A, Park MD, Pia L, Risson E, Saffern M, Salomé B, Esai Selvan M, Spindler MP, Tan J, van der Heide V, Gregory JK, Alexandropoulos K, Bhardwaj N, Brown BD, Greenbaum B, Gümüş ZH, Homann D, Horowitz A, Kamphorst AO, Curotto de Lafaille MA, Mehandru S, Merad M, Samstein RM; Sinai Immunology Review Project. Vabret N, et al. Immunity. 2020 Jun 16;52(6):910-941. doi: 10.1016/j.immuni.2020.05.002. Epub 2020 May 6. Immunity. 2020. PMID: 32505227 Free PMC article. Review.
"America First" Will Destroy U.S. Science.
Brown BD, Leader AM, Vilcek J, Merad M. Brown BD, et al. Cell. 2020 Nov 12;183(4):841-844. doi: 10.1016/j.cell.2020.09.025. Epub 2020 Sep 18. Cell. 2020. PMID: 32949492 Free PMC article.
319 results