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RNA-Mediated Feedback Control of Transcriptional Condensates.
Henninger JE, Oksuz O, Shrinivas K, Sagi I, LeRoy G, Zheng MM, Andrews JO, Zamudio AV, Lazaris C, Hannett NM, Lee TI, Sharp PA, Cissé II, Chakraborty AK, Young RA. Henninger JE, et al. Among authors: leroy g. Cell. 2021 Jan 7;184(1):207-225.e24. doi: 10.1016/j.cell.2020.11.030. Epub 2020 Dec 16. Cell. 2021. PMID: 33333019 Free PMC article.
MeCP2 links heterochromatin condensates and neurodevelopmental disease.
Li CH, Coffey EL, Dall'Agnese A, Hannett NM, Tang X, Henninger JE, Platt JM, Oksuz O, Zamudio AV, Afeyan LK, Schuijers J, Liu XS, Markoulaki S, Lungjangwa T, LeRoy G, Svoboda DS, Wogram E, Lee TI, Jaenisch R, Young RA. Li CH, et al. Among authors: leroy g. Nature. 2020 Oct;586(7829):440-444. doi: 10.1038/s41586-020-2574-4. Epub 2020 Jul 22. Nature. 2020. PMID: 32698189 Free PMC article.
Capturing the Onset of PRC2-Mediated Repressive Domain Formation.
Oksuz O, Narendra V, Lee CH, Descostes N, LeRoy G, Raviram R, Blumenberg L, Karch K, Rocha PP, Garcia BA, Skok JA, Reinberg D. Oksuz O, et al. Among authors: leroy g. Mol Cell. 2018 Jun 21;70(6):1149-1162.e5. doi: 10.1016/j.molcel.2018.05.023. Mol Cell. 2018. PMID: 29932905 Free PMC article.
Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2.
Modrek AS, Golub D, Khan T, Bready D, Prado J, Bowman C, Deng J, Zhang G, Rocha PP, Raviram R, Lazaris C, Stafford JM, LeRoy G, Kader M, Dhaliwal J, Bayin NS, Frenster JD, Serrano J, Chiriboga L, Baitalmal R, Nanjangud G, Chi AS, Golfinos JG, Wang J, Karajannis MA, Bonneau RA, Reinberg D, Tsirigos A, Zagzag D, Snuderl M, Skok JA, Neubert TA, Placantonakis DG. Modrek AS, et al. Among authors: leroy g. Cell Rep. 2017 Oct 31;21(5):1267-1280. doi: 10.1016/j.celrep.2017.10.009. Cell Rep. 2017. PMID: 29091765 Free PMC article.
Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma.
Stafford JM, Lee CH, Voigt P, Descostes N, Saldaña-Meyer R, Yu JR, Leroy G, Oksuz O, Chapman JR, Suarez F, Modrek AS, Bayin NS, Placantonakis DG, Karajannis MA, Snuderl M, Ueberheide B, Reinberg D. Stafford JM, et al. Among authors: leroy g. Sci Adv. 2018 Oct 31;4(10):eaau5935. doi: 10.1126/sciadv.aau5935. eCollection 2018 Oct. Sci Adv. 2018. PMID: 30402543 Free PMC article.
Asymmetrically modified nucleosomes.
Voigt P, LeRoy G, Drury WJ 3rd, Zee BM, Son J, Beck DB, Young NL, Garcia BA, Reinberg D. Voigt P, et al. Among authors: leroy g. Cell. 2012 Sep 28;151(1):181-93. doi: 10.1016/j.cell.2012.09.002. Cell. 2012. PMID: 23021224 Free PMC article.
Chromatin Starts to Come Clean.
Tu S, LeRoy G, Reinberg D. Tu S, et al. Among authors: leroy g. Mol Cell. 2016 Nov 3;64(3):439-441. doi: 10.1016/j.molcel.2016.10.022. Mol Cell. 2016. PMID: 27814489 Free article.
361 results