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PCSK9 regulates the NODAL signaling pathway and cellular proliferation in hiPSCs.
Roudaut M, Idriss S, Caillaud A, Girardeau A, Rimbert A, Champon B, David A, Lévêque A, Arnaud L, Pichelin M, Prieur X, Prat A, Seidah NG, Zibara K, Le May C, Cariou B, Si-Tayeb K. Roudaut M, et al. Among authors: le may c. Stem Cell Reports. 2021 Dec 14;16(12):2958-2972. doi: 10.1016/j.stemcr.2021.10.004. Epub 2021 Nov 4. Stem Cell Reports. 2021. PMID: 34739847 Free PMC article.
PCSK9 dominant negative mutant results in increased LDL catabolic rate and familial hypobetalipoproteinemia.
Cariou B, Ouguerram K, Zaïr Y, Guerois R, Langhi C, Kourimate S, Benoit I, Le May C, Gayet C, Belabbas K, Dufernez F, Chétiveaux M, Tarugi P, Krempf M, Benlian P, Costet P. Cariou B, et al. Among authors: le may c. Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2191-7. doi: 10.1161/ATVBAHA.109.194191. Epub 2009 Sep 17. Arterioscler Thromb Vasc Biol. 2009. PMID: 19762784
PCSK9 is expressed in pancreatic delta-cells and does not alter insulin secretion.
Langhi C, Le May C, Gmyr V, Vandewalle B, Kerr-Conte J, Krempf M, Pattou F, Costet P, Cariou B. Langhi C, et al. Among authors: le may c. Biochem Biophys Res Commun. 2009 Dec 25;390(4):1288-93. doi: 10.1016/j.bbrc.2009.10.138. Epub 2009 Oct 28. Biochem Biophys Res Commun. 2009. PMID: 19878649
Clinical aspects of PCSK9.
Cariou B, Le May C, Costet P. Cariou B, et al. Among authors: le may c. Atherosclerosis. 2011 Jun;216(2):258-65. doi: 10.1016/j.atherosclerosis.2011.04.018. Epub 2011 Apr 22. Atherosclerosis. 2011. PMID: 21596380 Review.
Plasma PCSK9 concentrations during an oral fat load and after short term high-fat, high-fat high-protein and high-fructose diets.
Cariou B, Langhi C, Le Bras M, Bortolotti M, Lê KA, Theytaz F, Le May C, Guyomarc'h-Delasalle B, Zaïr Y, Kreis R, Boesch C, Krempf M, Tappy L, Costet P. Cariou B, et al. Among authors: le bras m, le may c, le ka. Nutr Metab (Lond). 2013 Jan 8;10(1):4. doi: 10.1186/1743-7075-10-4. Nutr Metab (Lond). 2013. PMID: 23298392 Free PMC article.
105 results