Le Guillou D - Search Results

1

Chronic exposure to low doses of pharmaceuticals disturbs the hepatic expression of circadian genes in lean and obese mice.

Anthérieu S, Le Guillou D, Coulouarn C, Begriche K, Trak-Smayra V, Martinais S, Porceddu M, Robin MA, Fromenty B. Anthérieu S, et al. Among authors: le guillou d. Toxicol Appl Pharmacol. 2014 Apr 1;276(1):63-72. doi: 10.1016/j.taap.2014.01.019. Epub 2014 Feb 11. Toxicol Appl Pharmacol. 2014. PMID: 24525044 Free article.

2

A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophen.

Michaut A, Le Guillou D, Moreau C, Bucher S, McGill MR, Martinais S, Gicquel T, Morel I, Robin MA, Jaeschke H, Fromenty B. Michaut A, et al. Among authors: le guillou d. Toxicol Appl Pharmacol. 2016 Feb 1;292:40-55. doi: 10.1016/j.taap.2015.12.020. Epub 2015 Dec 29. Toxicol Appl Pharmacol. 2016. PMID: 26739624 Free PMC article.

3

Bisphenol a induces steatosis in HepaRG cells using a model of perinatal exposure.

Bucher S, Jalili P, Le Guillou D, Begriche K, Rondel K, Martinais S, Zalko D, Corlu A, Robin MA, Fromenty B. Bucher S, et al. Among authors: le guillou d. Environ Toxicol. 2017 Mar;32(3):1024-1036. doi: 10.1002/tox.22301. Epub 2016 Jun 20. Environ Toxicol. 2017. PMID: 27322340 Free article.

4

Drug-Induced Alterations of Mitochondrial DNA Homeostasis in Steatotic and Nonsteatotic HepaRG Cells.

Le Guillou D, Bucher S, Begriche K, Hoët D, Lombès A, Labbe G, Fromenty B. Le Guillou D, et al. J Pharmacol Exp Ther. 2018 Jun;365(3):711-726. doi: 10.1124/jpet.117.246751. Epub 2018 Apr 18. J Pharmacol Exp Ther. 2018. PMID: 29669730 Free article.

5

Drug-induced liver injury in obesity and nonalcoholic fatty liver disease.

Allard J, Le Guillou D, Begriche K, Fromenty B. Allard J, et al. Among authors: le guillou d. Adv Pharmacol. 2019;85:75-107. doi: 10.1016/bs.apha.2019.01.003. Epub 2019 Feb 20. Adv Pharmacol. 2019. PMID: 31307592 Review.

6

Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity.

Allard J, Bucher S, Massart J, Ferron PJ, Le Guillou D, Loyant R, Daniel Y, Launay Y, Buron N, Begriche K, Borgne-Sanchez A, Fromenty B. Allard J, et al. Among authors: le guillou d. Cell Biol Toxicol. 2021 Apr;37(2):151-175. doi: 10.1007/s10565-020-09537-1. Epub 2020 Jun 14. Cell Biol Toxicol. 2021. PMID: 32535746 Free PMC article.

7

Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo.

Bucher S, Tête A, Podechard N, Liamin M, Le Guillou D, Chevanne M, Coulouarn C, Imran M, Gallais I, Fernier M, Hamdaoui Q, Robin MA, Sergent O, Fromenty B, Lagadic-Gossmann D. Bucher S, et al. Among authors: le guillou d. Sci Rep. 2018 Apr 13;8(1):5963. doi: 10.1038/s41598-018-24403-1. Sci Rep. 2018. PMID: 29654281 Free PMC article.

8

Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure.

Bucher S, Le Guillou D, Allard J, Pinon G, Begriche K, Tête A, Sergent O, Lagadic-Gossmann D, Fromenty B. Bucher S, et al. Among authors: le guillou d. Oxid Med Cell Longev. 2018 Jul 26;2018:4396403. doi: 10.1155/2018/4396403. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 30147834 Free PMC article.

9

Endotoxin regulates matrix genes increasing reactive oxygen species generation by intercellular communication between palmitate-treated hepatocyte and stellate cell.

Dornas W, Glaise D, Bodin A, Sharanek A, Burban A, Le Guillou D, Robert S, Dutertre S, Aninat C, Corlu A, Lagente V. Dornas W, et al. Among authors: le guillou d. J Cell Physiol. 2018 Jan;234(1):122-133. doi: 10.1002/jcp.27175. Epub 2018 Sep 7. J Cell Physiol. 2018. PMID: 30191979

10

Induced Pluripotent Stem Cell-derived Hepatocytes From Patients With Nonalcoholic Fatty Liver Disease Display a Disease-specific Gene Expression Profile.

Duwaerts CC, Le Guillou D, Her CL, Phillips NJ, Willenbring H, Mattis AN, Maher JJ. Duwaerts CC, et al. Among authors: le guillou d. Gastroenterology. 2021 Jun;160(7):2591-2594.e6. doi: 10.1053/j.gastro.2021.02.050. Epub 2021 Feb 25. Gastroenterology. 2021. PMID: 33640436 Free PMC article. No abstract available.

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