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AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration.
Crosas-Molist E, Graziani V, Maiques O, Pandya P, Monger J, Samain R, George SL, Malik S, Salise J, Morales V, Le Guennec A, Atkinson RA, Marti RM, Matias-Guiu X, Charras G, Conte MR, Elosegui-Artola A, Holt M, Sanz-Moreno V. Crosas-Molist E, et al. Among authors: le guennec a. Nat Commun. 2023 May 22;14(1):2740. doi: 10.1038/s41467-023-38292-0. Nat Commun. 2023. PMID: 37217519 Free PMC article.
Microbial functional change is linked with clinical outcomes after capsular fecal transplant in cirrhosis.
Bajaj JS, Salzman N, Acharya C, Takei H, Kakiyama G, Fagan A, White MB, Gavis EA, Holtz ML, Hayward M, Nittono H, Hylemon PB, Cox IJ, Williams R, Taylor-Robinson SD, Sterling RK, Matherly SC, Fuchs M, Lee H, Puri P, Stravitz RT, Sanyal AJ, Ajayi L, Le Guennec A, Atkinson RA, Siddiqui MS, Luketic V, Pandak WM, Sikaroodi M, Gillevet PM. Bajaj JS, et al. Among authors: le guennec a. JCI Insight. 2019 Dec 19;4(24):e133410. doi: 10.1172/jci.insight.133410. JCI Insight. 2019. PMID: 31751317 Free PMC article. Clinical Trial.
Metabolomics and microbial composition increase insight into the impact of dietary differences in cirrhosis.
Cox IJ, Idilman R, Fagan A, Turan D, Ajayi L, Le Guennec AD, Taylor-Robinson SD, Karakaya F, Gavis E, Andrew Atkinson R, Williams R, Sikaroodi M, Nizam S, Gillevet PM, Bajaj JS. Cox IJ, et al. Among authors: le guennec ad. Liver Int. 2020 Feb;40(2):416-427. doi: 10.1111/liv.14256. Epub 2019 Oct 7. Liver Int. 2020. PMID: 31544308 Free PMC article.
Partial MCT1 invalidation protects against diet-induced non-alcoholic fatty liver disease and the associated brain dysfunction.
Hadjihambi A, Konstantinou C, Klohs J, Monsorno K, Le Guennec A, Donnelly C, Cox IJ, Kusumbe A, Hosford PS, Soffientini U, Lecca S, Mameli M, Jalan R, Paolicelli RC, Pellerin L. Hadjihambi A, et al. Among authors: le guennec a. J Hepatol. 2023 Jan;78(1):180-190. doi: 10.1016/j.jhep.2022.08.008. Epub 2022 Aug 19. J Hepatol. 2023. PMID: 35995127 Free article.
Rat liver extracellular matrix and perfusion bioreactor culture promote human amnion epithelial cell differentiation towards hepatocyte-like cells.
Campinoti S, Almeida B, Goudarzi N, Bencina S, Grundland Freile F, McQuitty C, Natarajan D, Cox IJ, Le Guennec A, Khati V, Gaudenzi G, Gramignoli R, Urbani L. Campinoti S, et al. Among authors: le guennec a. J Tissue Eng. 2023 Dec 22;14:20417314231219813. doi: 10.1177/20417314231219813. eCollection 2023 Jan-Dec. J Tissue Eng. 2023. PMID: 38143931 Free PMC article.
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