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Design and Microwave Synthesis of New (5Z) 5-Arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5Z) 2-Amino-5-arylidene-1,3-thiazol-4(5H)-one as New Inhibitors of Protein Kinase DYRK1A.
Bourahla K, Guihéneuf S, Limanton E, Paquin L, Le Guével R, Charlier T, Rahmouni M, Durieu E, Lozach O, Carreaux F, Meijer L, Bazureau JP. Bourahla K, et al. Among authors: le guevel r. Pharmaceuticals (Basel). 2021 Oct 27;14(11):1086. doi: 10.3390/ph14111086. Pharmaceuticals (Basel). 2021. PMID: 34832868 Free PMC article.
Automated detection of hepatotoxic compounds in human hepatocytes using HepaRG cells and image-based analysis of mitochondrial dysfunction with JC-1 dye.
Pernelle K, Le Guevel R, Glaise D, Stasio CG, Le Charpentier T, Bouaita B, Corlu A, Guguen-Guillouzo C. Pernelle K, et al. Among authors: le guevel r, le charpentier t. Toxicol Appl Pharmacol. 2011 Aug 1;254(3):256-66. doi: 10.1016/j.taap.2011.04.018. Epub 2011 May 4. Toxicol Appl Pharmacol. 2011. PMID: 21569786
Synthesis and biological evaluation of 3-amino-, 3-alkoxy- and 3-aryloxy-6-(hetero)arylpyridazines as potent antitumor agents.
Sengmany S, Sitter M, Léonel E, Le Gall E, Loirand G, Martens T, Dubreuil D, Dilasser F, Rousselle M, Sauzeau V, Lebreton J, Pipelier M, Le Guével R. Sengmany S, et al. Among authors: le guevel r, le gall e. Bioorg Med Chem Lett. 2019 Mar 1;29(5):755-760. doi: 10.1016/j.bmcl.2018.12.050. Epub 2018 Dec 23. Bioorg Med Chem Lett. 2019. PMID: 30655216 Free article.
De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas.
Mebarki S, Désert R, Sulpice L, Sicard M, Desille M, Canal F, Dubois-Pot Schneider H, Bergeat D, Turlin B, Bellaud P, Lavergne E, Le Guével R, Corlu A, Perret C, Coulouarn C, Clément B, Musso O. Mebarki S, et al. Among authors: le guevel r. Oncotarget. 2016 Jun 28;7(26):39026-39043. doi: 10.18632/oncotarget.9346. Oncotarget. 2016. PMID: 27191501 Free PMC article.
47 results