Le Grice SFJ - Search Results

1

Recent Advances in Targeting the HIV-1 Tat/TAR Complex.

Abulwerdi FA, Le Grice SFJ. Abulwerdi FA, et al. Among authors: le grice sfj. Curr Pharm Des. 2017;23(28):4112-4121. doi: 10.2174/1381612823666170616081736. Curr Pharm Des. 2017. PMID: 28625133 Review.

2

Development of Small Molecules with a Noncanonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA.

Abulwerdi FA, Shortridge MD, Sztuba-Solinska J, Wilson R, Le Grice SF, Varani G, Schneekloth JS Jr. Abulwerdi FA, et al. J Med Chem. 2016 Dec 22;59(24):11148-11160. doi: 10.1021/acs.jmedchem.6b01450. Epub 2016 Dec 2. J Med Chem. 2016. PMID: 28002966 Free PMC article.

3

Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1.

Abulwerdi FA, Xu W, Ageeli AA, Yonkunas MJ, Arun G, Nam H, Schneekloth JS Jr, Dayie TK, Spector D, Baird N, Le Grice SFJ. Abulwerdi FA, et al. Among authors: le grice sfj. ACS Chem Biol. 2019 Feb 15;14(2):223-235. doi: 10.1021/acschembio.8b00807. Epub 2019 Jan 31. ACS Chem Biol. 2019. PMID: 30620551 Free PMC article.

4

Structural insights of the conserved "priming loop" of hepatitis B virus pre-genomic RNA.

LeBlanc RM, Kasprzak WK, Longhini AP, Olenginski LT, Abulwerdi F, Ginocchio S, Shields B, Nyman J, Svirydava M, Del Vecchio C, Ivanic J, Schneekloth JS Jr, Shapiro BA, Dayie TK, Le Grice SFJ. LeBlanc RM, et al. Among authors: le grice sfj. J Biomol Struct Dyn. 2022;40(20):9761-9773. doi: 10.1080/07391102.2021.1934544. Epub 2021 Jun 22. J Biomol Struct Dyn. 2022. PMID: 34155954 Free PMC article.

5

Dysregulation of Hepatitis B Virus Nucleocapsid Assembly in vitro by RNA-binding Small Ligands.

Patel N, Abulwerdi F, Fatehi F, Manfield IW, Le Grice S, Schneekloth JS Jr, Twarock R, Stockley PG. Patel N, et al. J Mol Biol. 2022 May 30;434(10):167557. doi: 10.1016/j.jmb.2022.167557. Epub 2022 Mar 24. J Mol Biol. 2022. PMID: 35341740 Free PMC article.

6

Dataset of high-throughput ligand screening against the RNA Packaging Signals regulating Hepatitis B Virus nucleocapsid formation.

Abulwerdi F, Fatehi F, Manfield IW, Le Grice SFJ, Schneekloth JS, Twarock R, Stockley PG, Patel N. Abulwerdi F, et al. Among authors: le grice sfj. Data Brief. 2022 Apr 26;42:108206. doi: 10.1016/j.dib.2022.108206. eCollection 2022 Jun. Data Brief. 2022. PMID: 35516001 Free PMC article.

7

An Evolved RNA Recognition Motif That Suppresses HIV-1 Tat/TAR-Dependent Transcription.

Crawford DW, Blakeley BD, Chen PH, Sherpa C, Le Grice SF, Laird-Offringa IA, McNaughton BR. Crawford DW, et al. ACS Chem Biol. 2016 Aug 19;11(8):2206-15. doi: 10.1021/acschembio.6b00145. Epub 2016 Jun 13. ACS Chem Biol. 2016. PMID: 27253715 Free PMC article.

8

Targeting the HIV RNA genome: high-hanging fruit only needs a longer ladder.

Le Grice SF. Le Grice SF. Curr Top Microbiol Immunol. 2015;389:147-69. doi: 10.1007/82_2015_434. Curr Top Microbiol Immunol. 2015. PMID: 25735922 Free PMC article. Review.

9

Identification of biologically active, HIV TAR RNA-binding small molecules using small molecule microarrays.

Sztuba-Solinska J, Shenoy SR, Gareiss P, Krumpe LR, Le Grice SF, O'Keefe BR, Schneekloth JS Jr. Sztuba-Solinska J, et al. J Am Chem Soc. 2014 Jun 11;136(23):8402-10. doi: 10.1021/ja502754f. Epub 2014 May 28. J Am Chem Soc. 2014. PMID: 24820959 Free PMC article.

10

Characterizing the Latent HIV-1 Reservoir in Patients with Viremia Suppressed on cART: Progress, Challenges, and Opportunities.

Rausch JW, Le Grice SFJ. Rausch JW, et al. Among authors: le grice sfj. Curr HIV Res. 2020;18(2):99-113. doi: 10.2174/1570162X18666191231105438. Curr HIV Res. 2020. PMID: 31889490 Free PMC article.

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