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ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma.
Jackson ER, Duchatel RJ, Staudt DE, Persson ML, Mannan A, Yadavilli S, Parackal S, Game S, Chong WC, Jayasekara WSN, Le Grand M, Kearney PS, Douglas AM, Findlay IJ, Germon ZP, McEwen HP, Beitaki TS, Patabendige A, Skerrett-Byrne DA, Nixon B, Smith ND, Day B, Manoharan N, Nagabushan S, Hansford JR, Govender D, McCowage GB, Firestein R, Howlett M, Endersby R, Gottardo NG, Alvaro F, Waszak SM, Larsen MR, Colino-Sanguino Y, Valdés-Mora F, Rakotomalala A, Meignan S, Pasquier E, Andre N, Hulleman E, Eisenstat DD, Vitanza NA, Nazarian J, Koschmann C, Mueller S, Cain JE, Dun MD. Jackson ER, et al. Among authors: le grand m. Cancer Res. 2023 May 5;83(14):2421-37. doi: 10.1158/0008-5472.CAN-23-0186. Online ahead of print. Cancer Res. 2023. PMID: 37145169 Free PMC article.
Combination drug screen targeting glioblastoma core vulnerabilities reveals pharmacological synergisms.
Ariey-Bonnet J, Berges R, Montero MP, Mouysset B, Piris P, Muller K, Pinna G, Failes TW, Arndt GM, Morando P, Baeza-Kallee N, Colin C, Chinot O, Braguer D, Morelli X, André N, Carré M, Tabouret E, Figarella-Branger D, Le Grand M, Pasquier E. Ariey-Bonnet J, et al. Among authors: le grand m. EBioMedicine. 2023 Sep;95:104752. doi: 10.1016/j.ebiom.2023.104752. Epub 2023 Aug 10. EBioMedicine. 2023. PMID: 37572644 Free PMC article.
In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor.
Ariey-Bonnet J, Carrasco K, Le Grand M, Hoffer L, Betzi S, Feracci M, Tsvetkov P, Devred F, Collette Y, Morelli X, Ballester P, Pasquier E. Ariey-Bonnet J, et al. Among authors: le grand m. Mol Oncol. 2020 Dec;14(12):3083-3099. doi: 10.1002/1878-0261.12810. Epub 2020 Oct 18. Mol Oncol. 2020. PMID: 33021050 Free PMC article.
Poly-pharmacology of existing drugs: How to crack the code?
Mouysset B, Le Grand M, Camoin L, Pasquier E. Mouysset B, et al. Among authors: le grand m. Cancer Lett. 2024 Apr 28;588:216800. doi: 10.1016/j.canlet.2024.216800. Epub 2024 Mar 14. Cancer Lett. 2024. PMID: 38492768 Free article. Review.
Game-based learning to improve diagnostic accuracy: a pilot randomized-controlled trial.
Morgan DJ, Scherer L, Pineles L, Baghdadi J, Magder L, Thom K, Koch C, Wilkins N, LeGrand M, Stevens D, Walker R, Shirrell B, Harris AD, Korenstein D. Morgan DJ, et al. Diagnosis (Berl). 2024 Jan 30;11(2):136-141. doi: 10.1515/dx-2023-0133. eCollection 2024 May 1. Diagnosis (Berl). 2024. PMID: 38284830 Free PMC article. Clinical Trial.
37 results