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Broad-spectrum non-toxic antiviral nanoparticles with a virucidal inhibition mechanism.
Cagno V, Andreozzi P, D'Alicarnasso M, Jacob Silva P, Mueller M, Galloux M, Le Goffic R, Jones ST, Vallino M, Hodek J, Weber J, Sen S, Janeček ER, Bekdemir A, Sanavio B, Martinelli C, Donalisio M, Rameix Welti MA, Eleouet JF, Han Y, Kaiser L, Vukovic L, Tapparel C, Král P, Krol S, Lembo D, Stellacci F. Cagno V, et al. Among authors: le goffic r. Nat Mater. 2018 Feb;17(2):195-203. doi: 10.1038/nmat5053. Epub 2017 Dec 18. Nat Mater. 2018. PMID: 29251725 Free article.
Non-Toxic Virucidal Macromolecules Show High Efficacy Against Influenza Virus Ex Vivo and In Vivo.
Kocabiyik O, Cagno V, Silva PJ, Zhu Y, Sedano L, Bhide Y, Mettier J, Medaglia C, Da Costa B, Constant S, Huang S, Kaiser L, Hinrichs WLJ, Huckriede A, Le Goffic R, Tapparel C, Stellacci F. Kocabiyik O, et al. Among authors: le goffic r. Adv Sci (Weinh). 2020 Dec 14;8(3):2001012. doi: 10.1002/advs.202001012. eCollection 2021 Feb. Adv Sci (Weinh). 2020. PMID: 33552848 Free PMC article.
Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein.
Guillon A, Brea-Diakite D, Cezard A, Wacquiez A, Baranek T, Bourgeais J, Picou F, Vasseur V, Meyer L, Chevalier C, Auvet A, Carballido JM, Nadal Desbarats L, Dingli F, Turtoi A, Le Gouellec A, Fauvelle F, Donchet A, Crépin T, Hiemstra PS, Paget C, Loew D, Herault O, Naffakh N, Le Goffic R, Si-Tahar M. Guillon A, et al. Among authors: le goffic r. EMBO J. 2022 Jun 14;41(12):e108306. doi: 10.15252/embj.2021108306. Epub 2022 May 4. EMBO J. 2022. PMID: 35506364 Free PMC article.
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor.
Sake SM, Zhang X, Rajak MK, Urbanek-Quaing M, Carpentier A, Gunesch AP, Grethe C, Matthaei A, Rückert J, Galloux M, Larcher T, Le Goffic R, Hontonnou F, Chatterjee AK, Johnson K, Morwood K, Rox K, Elgaher WAM, Huang J, Wetzke M, Hansen G, Fischer N, Eléouët JF, Rameix-Welti MA, Hirsch AKH, Herold E, Empting M, Lauber C, Schulz TF, Krey T, Haid S, Pietschmann T. Sake SM, et al. Among authors: le goffic r. Nat Commun. 2024 Feb 8;15(1):1173. doi: 10.1038/s41467-024-45241-y. Nat Commun. 2024. PMID: 38332002 Free PMC article. Review.
Infection with influenza virus induces IL-33 in murine lungs.
Le Goffic R, Arshad MI, Rauch M, L'Helgoualc'h A, Delmas B, Piquet-Pellorce C, Samson M. Le Goffic R, et al. Am J Respir Cell Mol Biol. 2011 Dec;45(6):1125-32. doi: 10.1165/rcmb.2010-0516OC. Epub 2011 Jun 3. Am J Respir Cell Mol Biol. 2011. PMID: 21642589
55 results