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Page 1
NAD+ Repletion Rescues Female Fertility during Reproductive Aging.
Bertoldo MJ, Listijono DR, Ho WJ, Riepsamen AH, Goss DM, Richani D, Jin XL, Mahbub S, Campbell JM, Habibalahi A, Loh WN, Youngson NA, Maniam J, Wong ASA, Selesniemi K, Bustamante S, Li C, Zhao Y, Marinova MB, Kim LJ, Lau L, Wu RM, Mikolaizak AS, Araki T, Le Couteur DG, Turner N, Morris MJ, Walters KA, Goldys E, O'Neill C, Gilchrist RB, Sinclair DA, Homer HA, Wu LE. Bertoldo MJ, et al. Among authors: le couteur dg. Cell Rep. 2020 Feb 11;30(6):1670-1681.e7. doi: 10.1016/j.celrep.2020.01.058. Cell Rep. 2020. PMID: 32049001 Free PMC article.
The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice.
Solon-Biet SM, McMahon AC, Ballard JW, Ruohonen K, Wu LE, Cogger VC, Warren A, Huang X, Pichaud N, Melvin RG, Gokarn R, Khalil M, Turner N, Cooney GJ, Sinclair DA, Raubenheimer D, Le Couteur DG, Simpson SJ. Solon-Biet SM, et al. Among authors: le couteur dg. Cell Metab. 2014 Mar 4;19(3):418-30. doi: 10.1016/j.cmet.2014.02.009. Cell Metab. 2014. PMID: 24606899 Free PMC article.
Systemic VEGF-A neutralization ameliorates diet-induced metabolic dysfunction.
Wu LE, Meoli CC, Mangiafico SP, Fazakerley DJ, Cogger VC, Mohamad M, Pant H, Kang MJ, Powter E, Burchfield JG, Xirouchaki CE, Mikolaizak AS, Stöckli J, Kolumam G, van Bruggen N, Gamble JR, Le Couteur DG, Cooney GJ, Andrikopoulos S, James DE. Wu LE, et al. Among authors: le couteur dg. Diabetes. 2014 Aug;63(8):2656-67. doi: 10.2337/db13-1665. Epub 2014 Apr 2. Diabetes. 2014. PMID: 24696450
A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome.
Scheibye-Knudsen M, Mitchell SJ, Fang EF, Iyama T, Ward T, Wang J, Dunn CA, Singh N, Veith S, Hasan-Olive MM, Mangerich A, Wilson MA, Mattson MP, Bergersen LH, Cogger VC, Warren A, Le Couteur DG, Moaddel R, Wilson DM 3rd, Croteau DL, de Cabo R, Bohr VA. Scheibye-Knudsen M, et al. Among authors: le couteur dg. Cell Metab. 2014 Nov 4;20(5):840-855. doi: 10.1016/j.cmet.2014.10.005. Epub 2014 Nov 4. Cell Metab. 2014. PMID: 25440059 Free PMC article.
Macronutrient balance, reproductive function, and lifespan in aging mice.
Solon-Biet SM, Walters KA, Simanainen UK, McMahon AC, Ruohonen K, Ballard JW, Raubenheimer D, Handelsman DJ, Le Couteur DG, Simpson SJ. Solon-Biet SM, et al. Among authors: le couteur dg. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3481-6. doi: 10.1073/pnas.1422041112. Epub 2015 Mar 2. Proc Natl Acad Sci U S A. 2015. PMID: 25733862 Free PMC article.
Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age-related insulin resistance.
Mohamad M, Mitchell SJ, Wu LE, White MY, Cordwell SJ, Mach J, Solon-Biet SM, Boyer D, Nines D, Das A, Catherine Li SY, Warren A, Hilmer SN, Fraser R, Sinclair DA, Simpson SJ, de Cabo R, Le Couteur DG, Cogger VC. Mohamad M, et al. Among authors: le couteur dg. Aging Cell. 2016 Aug;15(4):706-15. doi: 10.1111/acel.12481. Epub 2016 Apr 20. Aging Cell. 2016. PMID: 27095270 Free PMC article.
Defining the Nutritional and Metabolic Context of FGF21 Using the Geometric Framework.
Solon-Biet SM, Cogger VC, Pulpitel T, Heblinski M, Wahl D, McMahon AC, Warren A, Durrant-Whyte J, Walters KA, Krycer JR, Ponton F, Gokarn R, Wali JA, Ruohonen K, Conigrave AD, James DE, Raubenheimer D, Morrison CD, Le Couteur DG, Simpson SJ. Solon-Biet SM, et al. Among authors: le couteur dg. Cell Metab. 2016 Oct 11;24(4):555-565. doi: 10.1016/j.cmet.2016.09.001. Epub 2016 Sep 29. Cell Metab. 2016. PMID: 27693377 Free article.
The Relationship Between Dietary Macronutrients and Hepatic Telomere Length in Aging Mice.
Gokarn R, Solon-Biet S, Youngson NA, Wahl D, Cogger VC, McMahon AC, Cooney GJ, Ballard JWO, Raubenheimer D, Morris MJ, Simpson SJ, Le Couteur DG. Gokarn R, et al. Among authors: le couteur dg. J Gerontol A Biol Sci Med Sci. 2018 Mar 14;73(4):446-449. doi: 10.1093/gerona/glx186. J Gerontol A Biol Sci Med Sci. 2018. PMID: 30052781
436 results