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51 results

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Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia.
Stuani L, Sabatier M, Saland E, Cognet G, Poupin N, Bosc C, Castelli FA, Gales L, Turtoi E, Montersino C, Farge T, Boet E, Broin N, Larrue C, Baran N, Cissé MY, Conti M, Loric S, Kaoma T, Hucteau A, Zavoriti A, Sahal A, Mouchel PL, Gotanègre M, Cassan C, Fernando L, Wang F, Hosseini M, Chu-Van E, Le Cam L, Carroll M, Selak MA, Vey N, Castellano R, Fenaille F, Turtoi A, Cazals G, Bories P, Gibon Y, Nicolay B, Ronseaux S, Marszalek JR, Takahashi K, DiNardo CD, Konopleva M, Pancaldi V, Collette Y, Bellvert F, Jourdan F, Linares LK, Récher C, Portais JC, Sarry JE. Stuani L, et al. Among authors: le cam l. J Exp Med. 2021 May 3;218(5):e20200924. doi: 10.1084/jem.20200924. J Exp Med. 2021. PMID: 33760042 Free PMC article.
Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia.
Boutzen H, Saland E, Larrue C, de Toni F, Gales L, Castelli FA, Cathebas M, Zaghdoudi S, Stuani L, Kaoma T, Riscal R, Yang G, Hirsch P, David M, De Mas-Mansat V, Delabesse E, Vallar L, Delhommeau F, Jouanin I, Ouerfelli O, Le Cam L, Linares LK, Junot C, Portais JC, Vergez F, Récher C, Sarry JE. Boutzen H, et al. Among authors: le cam l. J Exp Med. 2016 Apr 4;213(4):483-97. doi: 10.1084/jem.20150736. Epub 2016 Mar 7. J Exp Med. 2016. PMID: 26951332 Free PMC article. Clinical Trial.
[Role of the p53 tumor suppressor in metabolism].
Lacroix M, Linares LK, Le Cam L. Lacroix M, et al. Among authors: le cam l. Med Sci (Paris). 2013 Dec;29(12):1125-30. doi: 10.1051/medsci/20132912016. Epub 2013 Dec 20. Med Sci (Paris). 2013. PMID: 24356143 Free article. Review. French.
E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells.
Hatchi E, Rodier G, Lacroix M, Caramel J, Kirsh O, Jacquet C, Schrepfer E, Lagarrigue S, Linares LK, Lledo G, Tondeur S, Dubus P, Sardet C, Le Cam L. Hatchi E, et al. Among authors: le cam l. J Exp Med. 2011 Jul 4;208(7):1403-17. doi: 10.1084/jem.20101995. Epub 2011 Jun 27. J Exp Med. 2011. PMID: 21708927 Free PMC article.
Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.
Riscal R, Schrepfer E, Arena G, Cissé MY, Bellvert F, Heuillet M, Rambow F, Bonneil E, Sabourdy F, Vincent C, Ait-Arsa I, Levade T, Thibaut P, Marine JC, Portais JC, Sarry JE, Le Cam L, Linares LK. Riscal R, et al. Among authors: le cam l. Mol Cell. 2016 Jun 16;62(6):890-902. doi: 10.1016/j.molcel.2016.04.033. Epub 2016 Jun 2. Mol Cell. 2016. PMID: 27264869 Free article.
Chromatin-bound MDM2, a new player in metabolism.
Riscal R, Le Cam L, Linares LK. Riscal R, et al. Among authors: le cam l. Mol Cell Oncol. 2016 Jul 15;3(5):e1210560. doi: 10.1080/23723556.2016.1210560. eCollection 2016. Mol Cell Oncol. 2016. PMID: 27857973 Free PMC article.
Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma.
Cissé MY, Pyrdziak S, Firmin N, Gayte L, Heuillet M, Bellvert F, Fuentes M, Delpech H, Riscal R, Arena G, Chibon F, Le Gellec S, Maran-Gonzalez A, Chateau MC, Theillet C, Carrere S, Portais JC, Le Cam L, Linares LK. Cissé MY, et al. Among authors: le cam l. Sci Transl Med. 2020 Jun 10;12(547):eaay2163. doi: 10.1126/scitranslmed.aay2163. Sci Transl Med. 2020. PMID: 32522803
The p53 Pathway and Metabolism: The Tree That Hides the Forest.
Lahalle A, Lacroix M, De Blasio C, Cissé MY, Linares LK, Le Cam L. Lahalle A, et al. Among authors: le cam l. Cancers (Basel). 2021 Jan 4;13(1):133. doi: 10.3390/cancers13010133. Cancers (Basel). 2021. PMID: 33406607 Free PMC article. Review.
51 results