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Treatment of Mouse Sperm with a Non-Catalytic Mutant of PLA2G10 Reveals That PLA2G10 Improves In Vitro Fertilization through Both Its Enzymatic Activity and as Ligand of PLA2R1.
Abi Nahed R, Dhellemmes M, Payré C, Le Blévec E, Perrier JP, Hennebicq S, Escoffier J, Ray PF, Loeuillet C, Lambeau G, Arnoult C. Abi Nahed R, et al. Among authors: le blevec e. Int J Mol Sci. 2022 Jul 21;23(14):8033. doi: 10.3390/ijms23148033. Int J Mol Sci. 2022. PMID: 35887380 Free PMC article.
PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice.
Christou-Kent M, Kherraf ZE, Amiri-Yekta A, Le Blévec E, Karaouzène T, Conne B, Escoffier J, Assou S, Guttin A, Lambert E, Martinez G, Boguenet M, Fourati Ben Mustapha S, Cedrin Durnerin I, Halouani L, Marrakchi O, Makni M, Latrous H, Kharouf M, Coutton C, Thierry-Mieg N, Nef S, Bottari SP, Zouari R, Issartel JP, Ray PF, Arnoult C. Christou-Kent M, et al. Among authors: le blevec e. EMBO Mol Med. 2018 May;10(5):e8515. doi: 10.15252/emmm.201708515. EMBO Mol Med. 2018. PMID: 29661911 Free PMC article.