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Synthesis, Docking Studies and Pharmacological Evaluation of Serotoninergic Ligands Containing a 5-Norbornene-2-Carboxamide Nucleus.
Sparaco R, Kędzierska E, Kaczor AA, Bielenica A, Magli E, Severino B, Corvino A, Gibuła-Tarłowska E, Kotlińska JH, Andreozzi G, Luciano P, Perissutti E, Frecentese F, Casertano M, Leśniak A, Bujalska-Zadrożny M, Oziębło M, Capasso R, Santagada V, Caliendo G, Fiorino F. Sparaco R, et al. Among authors: lesniak a. Molecules. 2022 Oct 1;27(19):6492. doi: 10.3390/molecules27196492. Molecules. 2022. PMID: 36235029 Free PMC article.
Biological evaluation and molecular docking studies of AA3052, a compound containing a μ-selective opioid peptide agonist DALDA and d-Phe-Phe-d-Phe-Leu-Leu-NH2, a substance P analogue.
Kowalczyk A, Kleczkowska P, Rękawek M, Kulik K, Lesniak A, Erdei A, Borics A, Martin C, Pawlik K, Lipkowski AW, Benyhe S, Makulska-Nowak H, Ballet S, Bujalska-Zadrozny M. Kowalczyk A, et al. Among authors: lesniak a. Eur J Pharm Sci. 2016 Oct 10;93:11-20. doi: 10.1016/j.ejps.2016.07.009. Epub 2016 Jul 14. Eur J Pharm Sci. 2016. PMID: 27423260
Antinociceptive effect induced by a combination of opioid and neurotensin moieties vs. their hybrid peptide [Ile(9)]PK20 in an acute pain treatment in rodents.
Kleczkowska P, Hermans E, Kosson P, Kowalczyk A, Lesniak A, Pawlik K, Bojnik E, Benyhe S, Nowicka B, Bujalska-Zadrozny M, Misicka A, Lipkowski AW. Kleczkowska P, et al. Among authors: lesniak a. Brain Res. 2016 Oct 1;1648(Pt A):172-180. doi: 10.1016/j.brainres.2016.07.039. Epub 2016 Jul 26. Brain Res. 2016. PMID: 27473894
125 results