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Cardiolipin-deficient cells depend on anaplerotic pathways to ameliorate defective TCA cycle function.
Raja V, Salsaa M, Joshi AS, Li Y, van Roermund CWT, Saadat N, Lazcano P, Schmidtke M, Hüttemann M, Gupta SV, Wanders RJA, Greenberg ML. Raja V, et al. Among authors: lazcano p. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 May;1864(5):654-661. doi: 10.1016/j.bbalip.2019.02.001. Epub 2019 Feb 5. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 30731133 Free PMC article.
Corrigendum to "Cardiolipin-deficient cells depend on anaplerotic pathways to ameliorate defective TCA cycle function" [Biochim. Biophys. Acta, Mol. Cell Biol. Lipids 1864/5(2019) 654-661].
Raja V, Salsaa M, Joshi AS, Li Y, van Roermund CWT, Saadat N, Lazcano P, Schmidtke M, Hüttemann M, Gupta SV, Wanders RJA, Greenberg ML. Raja V, et al. Among authors: lazcano p. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Aug;1864(8):1183. doi: 10.1016/j.bbalip.2019.04.014. Epub 2019 May 4. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31060928 No abstract available.
NAD supplementation improves mitochondrial performance of cardiolipin mutants.
Ji J, Damschroder D, Bessert D, Lazcano P, Wessells R, Reynolds CA, Greenberg ML. Ji J, et al. Among authors: lazcano p. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Apr;1867(4):159094. doi: 10.1016/j.bbalip.2021.159094. Epub 2022 Jan 18. Biochim Biophys Acta Mol Cell Biol Lipids. 2022. PMID: 35051613 Free PMC article.
Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells.
Liang Z, Ralph-Epps T, Schmidtke MW, Lazcano P, Denis SW, Balážová M, Chakkour M, Hazime S, Ren M, Schlame M, Houtkooper RH, Greenberg ML. Liang Z, et al. Among authors: lazcano p. bioRxiv [Preprint]. 2024 Feb 4:2024.02.03.578755. doi: 10.1101/2024.02.03.578755. bioRxiv. 2024. PMID: 38352304 Free PMC article. Preprint.
Anomalous peroxidase activity of cytochrome c is the primary pathogenic target in Barth syndrome.
Kagan VE, Tyurina YY, Mikulska-Ruminska K, Damschroder D, Vieira Neto E, Lasorsa A, Kapralov AA, Tyurin VA, Amoscato AA, Samovich SN, Souryavong AB, Dar HH, Ramim A, Liang Z, Lazcano P, Ji J, Schmidtke MW, Kiselyov K, Korkmaz A, Vladimirov GK, Artyukhova MA, Rampratap P, Cole LK, Niyatie A, Baker EK, Peterson J, Hatch GM, Atkinson J, Vockley J, Kühn B, Wessells R, van der Wel PCA, Bahar I, Bayir H, Greenberg ML. Kagan VE, et al. Among authors: lazcano p. Nat Metab. 2023 Dec;5(12):2184-2205. doi: 10.1038/s42255-023-00926-4. Epub 2023 Nov 23. Nat Metab. 2023. PMID: 37996701
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