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Tumor-Related Molecular Mechanisms of Oxaliplatin Resistance.
Martinez-Balibrea E, Martínez-Cardús A, Ginés A, Ruiz de Porras V, Moutinho C, Layos L, Manzano JL, Bugés C, Bystrup S, Esteller M, Abad A. Martinez-Balibrea E, et al. Among authors: layos l. Mol Cancer Ther. 2015 Aug;14(8):1767-76. doi: 10.1158/1535-7163.MCT-14-0636. Epub 2015 Jul 16. Mol Cancer Ther. 2015. PMID: 26184483 Review.
UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy.
Martinez-Balibrea E, Abad A, Martínez-Cardús A, Ginés A, Valladares M, Navarro M, Aranda E, Marcuello E, Benavides M, Massutí B, Carrato A, Layos L, Manzano JL, Moreno V. Martinez-Balibrea E, et al. Among authors: layos l. Br J Cancer. 2010 Aug 10;103(4):581-9. doi: 10.1038/sj.bjc.6605776. Epub 2010 Jul 13. Br J Cancer. 2010. PMID: 20628391 Free PMC article. Clinical Trial.
Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway.
Ruiz de Porras V, Bystrup S, Martínez-Cardús A, Pluvinet R, Sumoy L, Howells L, James MI, Iwuji C, Manzano JL, Layos L, Bugés C, Abad A, Martínez-Balibrea E. Ruiz de Porras V, et al. Among authors: layos l. Sci Rep. 2016 Apr 19;6:24675. doi: 10.1038/srep24675. Sci Rep. 2016. PMID: 27091625 Free PMC article.
Resistant mechanisms to BRAF inhibitors in melanoma.
Manzano JL, Layos L, Bugés C, de Los Llanos Gil M, Vila L, Martínez-Balibrea E, Martínez-Cardús A. Manzano JL, et al. Among authors: layos l. Ann Transl Med. 2016 Jun;4(12):237. doi: 10.21037/atm.2016.06.07. Ann Transl Med. 2016. PMID: 27429963 Free PMC article. Review.
Tumor Expression of Cyclin-Dependent Kinase 5 (Cdk5) Is a Prognostic Biomarker and Predicts Outcome of Oxaliplatin-Treated Metastatic Colorectal Cancer Patients.
Ruiz de Porras V, Bystrup S, Cabrero-de Las Heras S, Musulén E, Palomero L, Alonso MH, Nieto R, Arango D, Moreno V, Queralt C, Manzano JL, Layos L, Bugés C, Martinez-Balibrea E. Ruiz de Porras V, et al. Among authors: layos l. Cancers (Basel). 2019 Oct 11;11(10):1540. doi: 10.3390/cancers11101540. Cancers (Basel). 2019. PMID: 31614664 Free PMC article.
Curcumin: A therapeutic strategy for colorectal cancer?
Ruiz de Porras V, Layos L, Martínez-Balibrea E. Ruiz de Porras V, et al. Among authors: layos l. Semin Cancer Biol. 2021 Aug;73:321-330. doi: 10.1016/j.semcancer.2020.09.004. Epub 2020 Sep 14. Semin Cancer Biol. 2021. PMID: 32942023 Review.
Modulation of DNA Damage Response by SAM and HD Domain Containing Deoxynucleoside Triphosphate Triphosphohydrolase (SAMHD1) Determines Prognosis and Treatment Efficacy in Different Solid Tumor Types.
Felip E, Gutiérrez-Chamorro L, Gómez M, Garcia-Vidal E, Romeo M, Morán T, Layos L, Pérez-Roca L, Riveira-Muñoz E, Clotet B, Fernandez PL, Mesía R, Martínez-Cardús A, Ballana E, Margelí M. Felip E, et al. Among authors: layos l. Cancers (Basel). 2022 Jan 27;14(3):641. doi: 10.3390/cancers14030641. Cancers (Basel). 2022. PMID: 35158911 Free PMC article.
21 results