Laybutt DR - Search Results

1

Phlda3 regulates beta cell survival during stress.

Bensellam M, Chan JY, Lee K, Joglekar MV, Hardikar AA, Loudovaris T, Thomas HE, Jonas JC, Laybutt DR. Bensellam M, et al. Among authors: laybutt dr. Sci Rep. 2019 Sep 6;9(1):12827. doi: 10.1038/s41598-019-49289-5. Sci Rep. 2019. PMID: 31492921 Free PMC article.

2

High glucose stimulates early response gene c-Myc expression in rat pancreatic beta cells.

Jonas JC, Laybutt DR, Steil GM, Trivedi N, Pertusa JG, Van de Casteele M, Weir GC, Henquin JC. Jonas JC, et al. Among authors: laybutt dr. J Biol Chem. 2001 Sep 21;276(38):35375-81. doi: 10.1074/jbc.M105020200. Epub 2001 Jul 16. J Biol Chem. 2001. PMID: 11457846 Free article.

3

Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia.

Laybutt DR, Kaneto H, Hasenkamp W, Grey S, Jonas JC, Sgroi DC, Groff A, Ferran C, Bonner-Weir S, Sharma A, Weir GC. Laybutt DR, et al. Diabetes. 2002 Feb;51(2):413-23. doi: 10.2337/diabetes.51.2.413. Diabetes. 2002. PMID: 11812749

4

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes.

Laybutt DR, Preston AM, Akerfeldt MC, Kench JG, Busch AK, Biankin AV, Biden TJ. Laybutt DR, et al. Diabetologia. 2007 Apr;50(4):752-63. doi: 10.1007/s00125-006-0590-z. Epub 2007 Feb 1. Diabetologia. 2007. PMID: 17268797

5

Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.

Akerfeldt MC, Howes J, Chan JY, Stevens VA, Boubenna N, McGuire HM, King C, Biden TJ, Laybutt DR. Akerfeldt MC, et al. Among authors: laybutt dr. Diabetes. 2008 Nov;57(11):3034-44. doi: 10.2337/db07-1802. Epub 2008 Jun 30. Diabetes. 2008. PMID: 18591394 Free PMC article.

6

Reduced endoplasmic reticulum (ER)-to-Golgi protein trafficking contributes to ER stress in lipotoxic mouse beta cells by promoting protein overload.

Preston AM, Gurisik E, Bartley C, Laybutt DR, Biden TJ. Preston AM, et al. Among authors: laybutt dr. Diabetologia. 2009 Nov;52(11):2369-2373. doi: 10.1007/s00125-009-1506-5. Epub 2009 Aug 29. Diabetologia. 2009. PMID: 19727664

7

Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets.

Cheng K, Ho K, Stokes R, Scott C, Lau SM, Hawthorne WJ, O'Connell PJ, Loudovaris T, Kay TW, Kulkarni RN, Okada T, Wang XL, Yim SH, Shah Y, Grey ST, Biankin AV, Kench JG, Laybutt DR, Gonzalez FJ, Kahn CR, Gunton JE. Cheng K, et al. Among authors: laybutt dr. J Clin Invest. 2010 Jun;120(6):2171-83. doi: 10.1172/JCI35846. Epub 2010 May 3. J Clin Invest. 2010. PMID: 20440072 Free PMC article.

8

Deletion of protein kinase Cδ in mice modulates stability of inflammatory genes and protects against cytokine-stimulated beta cell death in vitro and in vivo.

Cantley J, Boslem E, Laybutt DR, Cordery DV, Pearson G, Carpenter L, Leitges M, Biden TJ. Cantley J, et al. Among authors: laybutt dr. Diabetologia. 2011 Feb;54(2):380-9. doi: 10.1007/s00125-010-1962-y. Epub 2010 Nov 20. Diabetologia. 2011. PMID: 21103982

9

Differential regulation of adaptive and apoptotic unfolded protein response signalling by cytokine-induced nitric oxide production in mouse pancreatic beta cells.

Chan JY, Cooney GJ, Biden TJ, Laybutt DR. Chan JY, et al. Among authors: laybutt dr. Diabetologia. 2011 Jul;54(7):1766-76. doi: 10.1007/s00125-011-2139-z. Epub 2011 Apr 7. Diabetologia. 2011. PMID: 21472432

10

Glucose-induced O₂ consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cells.

Bensellam M, Duvillié B, Rybachuk G, Laybutt DR, Magnan C, Guiot Y, Pouysségur J, Jonas JC. Bensellam M, et al. Among authors: laybutt dr. PLoS One. 2012;7(1):e29807. doi: 10.1371/journal.pone.0029807. Epub 2012 Jan 3. PLoS One. 2012. PMID: 22235342 Free PMC article.

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