Lawton AJ - Search Results

1

SIRT3 deficiency decreases oxidative metabolism capacity but increases lifespan in male mice under caloric restriction.

Dhillon RS, Qin YA, van Ginkel PR, Fu VX, Vann JM, Lawton AJ, Green CL, Manchado-Gobatto FB, Gobatto CA, Lamming DW, Prolla TA, Denu JM. Dhillon RS, et al. Among authors: lawton aj. Aging Cell. 2022 Dec;21(12):e13721. doi: 10.1111/acel.13721. Epub 2022 Oct 5. Aging Cell. 2022. PMID: 36199173 Free PMC article.

2

Site-Specific Lysine Acetylation Stoichiometry Across Subcellular Compartments.

Lindahl AJ, Lawton AJ, Baeza J, Dowell JA, Denu JM. Lindahl AJ, et al. Among authors: lawton aj. Methods Mol Biol. 2019;1983:79-106. doi: 10.1007/978-1-4939-9434-2_6. Methods Mol Biol. 2019. PMID: 31087294

3

Acetyl-CoA flux regulates the proteome and acetyl-proteome to maintain intracellular metabolic crosstalk.

Dieterich IA, Lawton AJ, Peng Y, Yu Q, Rhoads TW, Overmyer KA, Cui Y, Armstrong EA, Howell PR, Burhans MS, Li L, Denu JM, Coon JJ, Anderson RM, Puglielli L. Dieterich IA, et al. Among authors: lawton aj. Nat Commun. 2019 Sep 2;10(1):3929. doi: 10.1038/s41467-019-11945-9. Nat Commun. 2019. PMID: 31477734 Free PMC article.

4

Revealing Dynamic Protein Acetylation across Subcellular Compartments.

Baeza J, Lawton AJ, Fan J, Smallegan MJ, Lienert I, Gandhi T, Bernhardt OM, Reiter L, Denu JM. Baeza J, et al. Among authors: lawton aj. J Proteome Res. 2020 Jun 5;19(6):2404-2418. doi: 10.1021/acs.jproteome.0c00088. Epub 2020 Apr 27. J Proteome Res. 2020. PMID: 32290654 Free PMC article.

5

Self-acetylation at the active site of phosphoenolpyruvate carboxykinase (PCK1) controls enzyme activity.

Latorre-Muro P, Baeza J, Hurtado-Guerrero R, Hicks T, Delso I, Hernández-Ruiz C, Velázquez-Campoy A, Lawton AJ, Angulo J, Denu JM, Carrodeguas JA. Latorre-Muro P, et al. Among authors: lawton aj. J Biol Chem. 2021 Jan-Jun;296:100205. doi: 10.1074/jbc.RA120.015103. Epub 2021 Jan 21. J Biol Chem. 2021. PMID: 33334880 Free PMC article.

6

Acetyl-CoA flux from the cytosol to the ER regulates engagement and quality of the secretory pathway.

Dieterich IA, Cui Y, Braun MM, Lawton AJ, Robinson NH, Peotter JL, Yu Q, Casler JC, Glick BS, Audhya A, Denu JM, Li L, Puglielli L. Dieterich IA, et al. Among authors: lawton aj. Sci Rep. 2021 Jan 21;11(1):2013. doi: 10.1038/s41598-021-81447-6. Sci Rep. 2021. PMID: 33479349 Free PMC article.

7

Endoplasmic reticulum acetyltransferases Atase1 and Atase2 differentially regulate reticulophagy, macroautophagy and cellular acetyl-CoA metabolism.

Rigby MJ, Lawton AJ, Kaur G, Banduseela VC, Kamm WE, Lakkaraju A, Denu JM, Puglielli L. Rigby MJ, et al. Among authors: lawton aj. Commun Biol. 2021 Apr 12;4(1):454. doi: 10.1038/s42003-021-01992-8. Commun Biol. 2021. PMID: 33846551 Free PMC article.

8

SLC13A5/sodium-citrate co-transporter overexpression causes disrupted white matter integrity and an autistic-like phenotype.

Rigby MJ, Orefice NS, Lawton AJ, Ma M, Shapiro SL, Yi SY, Dieterich IA, Frelka A, Miles HN, Pearce RA, Yu JPJ, Li L, Denu JM, Puglielli L. Rigby MJ, et al. Among authors: lawton aj. Brain Commun. 2022 Jan 5;4(1):fcac002. doi: 10.1093/braincomms/fcac002. eCollection 2022 Feb. Brain Commun. 2022. PMID: 35146426 Free PMC article.

9

Increased expression of SLC25A1/CIC causes an autistic-like phenotype with altered neuron morphology.

Rigby MJ, Orefice NS, Lawton AJ, Ma M, Shapiro SL, Yi SY, Dieterich IA, Frelka A, Miles HN, Pearce RA, Yu JPJ, Li L, Denu JM, Puglielli L. Rigby MJ, et al. Among authors: lawton aj. Brain. 2022 Apr 18;145(2):500-516. doi: 10.1093/brain/awab295. Brain. 2022. PMID: 35203088 Free PMC article.

10

The citrate transporters SLC13A5 and SLC25A1 elicit different metabolic responses and phenotypes in the mouse.

Fernandez-Fuente G, Overmyer KA, Lawton AJ, Kasza I, Shapiro SL, Gallego-Muñoz P, Coon JJ, Denu JM, Alexander CM, Puglielli L. Fernandez-Fuente G, et al. Among authors: lawton aj. Commun Biol. 2023 Sep 9;6(1):926. doi: 10.1038/s42003-023-05311-1. Commun Biol. 2023. PMID: 37689798 Free PMC article.

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