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Page 1
Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer.
Li R, Ferdinand JR, Loudon KW, Bowyer GS, Laidlaw S, Muyas F, Mamanova L, Neves JB, Bolt L, Fasouli ES, Lawson ARJ, Young MD, Hooks Y, Oliver TRW, Butler TM, Armitage JN, Aho T, Riddick ACP, Gnanapragasam V, Welsh SJ, Meyer KB, Warren AY, Tran MGB, Stewart GD, Cortés-Ciriano I, Behjati S, Clatworthy MR, Campbell PJ, Teichmann SA, Mitchell TJ. Li R, et al. Among authors: lawson arj. Cancer Cell. 2022 Dec 12;40(12):1583-1599.e10. doi: 10.1016/j.ccell.2022.11.001. Epub 2022 Nov 23. Cancer Cell. 2022. PMID: 36423636 Free PMC article.
Somatic mutant clones colonize the human esophagus with age.
Martincorena I, Fowler JC, Wabik A, Lawson ARJ, Abascal F, Hall MWJ, Cagan A, Murai K, Mahbubani K, Stratton MR, Fitzgerald RC, Handford PA, Campbell PJ, Saeb-Parsy K, Jones PH. Martincorena I, et al. Among authors: lawson arj. Science. 2018 Nov 23;362(6417):911-917. doi: 10.1126/science.aau3879. Epub 2018 Oct 18. Science. 2018. PMID: 30337457 Free PMC article.
Extensive heterogeneity in somatic mutation and selection in the human bladder.
Lawson ARJ, Abascal F, Coorens THH, Hooks Y, O'Neill L, Latimer C, Raine K, Sanders MA, Warren AY, Mahbubani KTA, Bareham B, Butler TM, Harvey LMR, Cagan A, Menzies A, Moore L, Colquhoun AJ, Turner W, Thomas B, Gnanapragasam V, Williams N, Rassl DM, Vöhringer H, Zumalave S, Nangalia J, Tubío JMC, Gerstung M, Saeb-Parsy K, Stratton MR, Campbell PJ, Mitchell TJ, Martincorena I. Lawson ARJ, et al. Science. 2020 Oct 2;370(6512):75-82. doi: 10.1126/science.aba8347. Science. 2020. PMID: 33004514
Extensive phylogenies of human development inferred from somatic mutations.
Coorens THH, Moore L, Robinson PS, Sanghvi R, Christopher J, Hewinson J, Przybilla MJ, Lawson ARJ, Spencer Chapman M, Cagan A, Oliver TRW, Neville MDC, Hooks Y, Noorani A, Mitchell TJ, Fitzgerald RC, Campbell PJ, Martincorena I, Rahbari R, Stratton MR. Coorens THH, et al. Among authors: lawson arj. Nature. 2021 Sep;597(7876):387-392. doi: 10.1038/s41586-021-03790-y. Epub 2021 Aug 25. Nature. 2021. PMID: 34433963
Somatic mutation rates scale with lifespan across mammals.
Cagan A, Baez-Ortega A, Brzozowska N, Abascal F, Coorens THH, Sanders MA, Lawson ARJ, Harvey LMR, Bhosle S, Jones D, Alcantara RE, Butler TM, Hooks Y, Roberts K, Anderson E, Lunn S, Flach E, Spiro S, Januszczak I, Wrigglesworth E, Jenkins H, Dallas T, Masters N, Perkins MW, Deaville R, Druce M, Bogeska R, Milsom MD, Neumann B, Gorman F, Constantino-Casas F, Peachey L, Bochynska D, Smith ESJ, Gerstung M, Campbell PJ, Murchison EP, Stratton MR, Martincorena I. Cagan A, et al. Among authors: lawson arj. Nature. 2022 Apr;604(7906):517-524. doi: 10.1038/s41586-022-04618-z. Epub 2022 Apr 13. Nature. 2022. PMID: 35418684 Free PMC article.
Author Correction: Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing.
Ellis P, Moore L, Sanders MA, Butler TM, Brunner SF, Lee-Six H, Osborne R, Farr B, Coorens THH, Lawson ARJ, Cagan A, Stratton MR, Martincorena I, Campbell PJ. Ellis P, et al. Among authors: lawson arj. Nat Protoc. 2023 Jun;18(6):1979. doi: 10.1038/s41596-023-00816-9. Nat Protoc. 2023. PMID: 36849600 No abstract available.
Haplotype-specific assembly of shattered chromosomes in esophageal adenocarcinomas.
Ijaz J, Harry E, Raine K, Menzies A, Beal K, Quail MA, Zumalave S, Jung H, Coorens THH, Lawson ARJ, Leongamornlert D, Francies HE, Garnett MJ, Ning Z, Campbell PJ. Ijaz J, et al. Among authors: lawson arj. Cell Genom. 2024 Feb 14;4(2):100484. doi: 10.1016/j.xgen.2023.100484. Epub 2024 Jan 16. Cell Genom. 2024. PMID: 38232733 Free PMC article.
Somatic mutation landscapes at single-molecule resolution.
Abascal F, Harvey LMR, Mitchell E, Lawson ARJ, Lensing SV, Ellis P, Russell AJC, Alcantara RE, Baez-Ortega A, Wang Y, Kwa EJ, Lee-Six H, Cagan A, Coorens THH, Chapman MS, Olafsson S, Leonard S, Jones D, Machado HE, Davies M, Øbro NF, Mahubani KT, Allinson K, Gerstung M, Saeb-Parsy K, Kent DG, Laurenti E, Stratton MR, Rahbari R, Campbell PJ, Osborne RJ, Martincorena I. Abascal F, et al. Among authors: lawson arj. Nature. 2021 May;593(7859):405-410. doi: 10.1038/s41586-021-03477-4. Epub 2021 Apr 28. Nature. 2021. PMID: 33911282 Free article.
Increased somatic mutation burdens in normal human cells due to defective DNA polymerases.
Robinson PS, Coorens THH, Palles C, Mitchell E, Abascal F, Olafsson S, Lee BCH, Lawson ARJ, Lee-Six H, Moore L, Sanders MA, Hewinson J, Martin L, Pinna CMA, Galavotti S, Rahbari R, Campbell PJ, Martincorena I, Tomlinson I, Stratton MR. Robinson PS, et al. Among authors: lawson arj. Nat Genet. 2021 Oct;53(10):1434-1442. doi: 10.1038/s41588-021-00930-y. Epub 2021 Sep 30. Nat Genet. 2021. PMID: 34594041 Free PMC article.
21 results