Lawson AD - Search Results

1

Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling.

Adams R, Burnley RJ, Valenzano CR, Qureshi O, Doyle C, Lumb S, Del Carmen Lopez M, Griffin R, McMillan D, Taylor RD, Meier C, Mori P, Griffin LM, Wernery U, Kinne J, Rapecki S, Baker TS, Lawson AD, Wright M, Ettorre A. Adams R, et al. Among authors: lawson ad. Sci Rep. 2017 Jan 30;7:37716. doi: 10.1038/srep37716. Sci Rep. 2017. PMID: 28134246 Free PMC article.

2

Humanization of an anti-mucin antibody for breast and ovarian cancer therapy.

Baker TS, Bose CC, Caskey-Finney HM, King DJ, Lawson AD, Lyons A, Mountain A, Owens RJ, Rolfe MR, Sehdev M, et al. Baker TS, et al. Among authors: lawson ad. Adv Exp Med Biol. 1994;353:61-82. doi: 10.1007/978-1-4615-2443-4_8. Adv Exp Med Biol. 1994. PMID: 7985543

3

Preparation and preclinical evaluation of humanised A33 immunoconjugates for radioimmunotherapy.

King DJ, Antoniw P, Owens RJ, Adair JR, Haines AM, Farnsworth AP, Finney H, Lawson AD, Lyons A, Baker TS, et al. King DJ, et al. Among authors: lawson ad. Br J Cancer. 1995 Dec;72(6):1364-72. doi: 10.1038/bjc.1995.516. Br J Cancer. 1995. PMID: 8519646 Free PMC article.

4

In vitro and in vivo characterisation of anti-murine IL-13 antibodies recognising distinct functional epitopes.

Berry LM, Adams R, Airey M, Bracher MG, Bourne T, Carrington B, Cross AS, Davies GC, Finney HM, Foulkes R, Gozzard N, Griffin RA, Hailu H, Lamour SD, Lawson AD, Lightwood DJ, McKnight AJ, O'Dowd VL, Oxbrow AK, Popplewell AG, Shaw S, Stephens PE, Sweeney B, Tomlinson KL, Uhe C, Palframan RT. Berry LM, et al. Among authors: lawson ad. Int Immunopharmacol. 2009 Feb;9(2):201-6. doi: 10.1016/j.intimp.2008.11.001. Epub 2008 Nov 27. Int Immunopharmacol. 2009. PMID: 19041426

5

Antibody fragments as tools in crystallography.

Griffin L, Lawson A. Griffin L, et al. Clin Exp Immunol. 2011 Sep;165(3):285-91. doi: 10.1111/j.1365-2249.2011.04427.x. Epub 2011 Jun 7. Clin Exp Immunol. 2011. PMID: 21649648 Free PMC article. Review.

6

Relative stabilities of IgG1 and IgG4 Fab domains: influence of the light-heavy interchain disulfide bond architecture.

Heads JT, Adams R, D'Hooghe LE, Page MJ, Humphreys DP, Popplewell AG, Lawson AD, Henry AJ. Heads JT, et al. Among authors: lawson ad. Protein Sci. 2012 Sep;21(9):1315-22. doi: 10.1002/pro.2118. Epub 2012 Aug 9. Protein Sci. 2012. PMID: 22761163 Free PMC article.

7

Conservation of functional sites on interleukin-6 and implications for evolution of signaling complex assembly and therapeutic intervention.

Veverka V, Baker T, Redpath NT, Carrington B, Muskett FW, Taylor RJ, Lawson AD, Henry AJ, Carr MD. Veverka V, et al. Among authors: lawson ad. J Biol Chem. 2012 Nov 16;287(47):40043-50. doi: 10.1074/jbc.M112.405597. Epub 2012 Oct 1. J Biol Chem. 2012. PMID: 23027872 Free PMC article.

8

¹⁵N, ¹³C and ¹H resonance assignments and secondary structure determination of a variable heavy domain of a heavy chain antibody.

Prosser CE, Waters LC, Muskett FW, Veverka V, Addis PW, Griffin LM, Baker TS, Lawson AD, Wernery U, Kinne J, Henry AJ, Taylor RJ, Carr MD. Prosser CE, et al. Among authors: lawson ad. Biomol NMR Assign. 2014 Apr;8(1):113-6. doi: 10.1007/s12104-013-9464-8. Epub 2013 Jan 29. Biomol NMR Assign. 2014. PMID: 23359223

9

Conformational heterogeneity in antibody-protein antigen recognition: implications for high affinity protein complex formation.

Addis PW, Hall CJ, Bruton S, Veverka V, Wilkinson IC, Muskett FW, Renshaw PS, Prosser CE, Carrington B, Lawson ADG, Griffin R, Taylor RJ, Waters LC, Henry AJ, Carr MD. Addis PW, et al. J Biol Chem. 2014 Mar 7;289(10):7200-7210. doi: 10.1074/jbc.M113.492215. Epub 2014 Jan 16. J Biol Chem. 2014. PMID: 24436329 Free PMC article.

10

Analysis of heavy and light chain sequences of conventional camelid antibodies from Camelus dromedarius and Camelus bactrianus species.

Griffin LM, Snowden JR, Lawson AD, Wernery U, Kinne J, Baker TS. Griffin LM, et al. Among authors: lawson ad. J Immunol Methods. 2014 Mar;405:35-46. doi: 10.1016/j.jim.2014.01.003. Epub 2014 Jan 18. J Immunol Methods. 2014. PMID: 24444705 Free article.

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