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204 results

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Population pharmacokinetics of liposomal amphotericin B in adults with HIV-associated cryptococcal meningoencephalitis.
Stott KE, Moyo M, Ahmadu A, Kajanga C, Gondwe E, Chimang'anga W, Chasweka M, Leeme TB, Molefi M, Chofle A, Bidwell G, Changalucha J, Unsworth J, Jimenez-Valverde A, Lawrence DS, Mwandumba HC, Lalloo DG, Harrison TS, Jarvis JN, Hope W, Märtson AG. Stott KE, et al. Among authors: lawrence ds. J Antimicrob Chemother. 2022 Dec 23;78(1):276-283. doi: 10.1093/jac/dkac389. J Antimicrob Chemother. 2022. PMID: 36411251 Free PMC article.
Short-course High-dose Liposomal Amphotericin B for Human Immunodeficiency Virus-associated Cryptococcal Meningitis: A Phase 2 Randomized Controlled Trial.
Jarvis JN, Leeme TB, Molefi M, Chofle AA, Bidwell G, Tsholo K, Tlhako N, Mawoko N, Patel RKK, Tenforde MW, Muthoga C, Bisson GP, Kidola J, Changalucha J, Lawrence D, Jaffar S, Hope W, Molloy SLF, Harrison TS. Jarvis JN, et al. Clin Infect Dis. 2019 Jan 18;68(3):393-401. doi: 10.1093/cid/ciy515. Clin Infect Dis. 2019. PMID: 29945252 Free PMC article. Clinical Trial.
AMBIsome Therapy Induction OptimisatioN (AMBITION): High dose AmBisome for cryptococcal meningitis induction therapy in sub-Saharan Africa: economic evaluation protocol for a randomised controlled trial-based equivalence study.
Ponatshego PL, Lawrence DS, Youssouf N, Molloy SF, Alufandika M, Bango F, Boulware DR, Chawinga C, Dziwani E, Gondwe E, Hlupeni A, Hosseinipour MC, Kanyama C, Meya DB, Mosepele M, Muthoga C, Muzoora CK, Mwandumba H, Ndhlovu CE, Rajasingham R, Sayed S, Shamu S, Tsholo K, Tugume L, Williams D, Maheswaran H, Shiri T, Boyer-Chammard T, Loyse A, Chen T, Wang D, Lortholary O, Lalloo DG, Meintjes G, Jaffar S, Harrison TS, Jarvis JN, Niessen LW. Ponatshego PL, et al. Among authors: lawrence ds. BMJ Open. 2019 Apr 1;9(4):e026288. doi: 10.1136/bmjopen-2018-026288. BMJ Open. 2019. PMID: 30940760 Free PMC article. Clinical Trial.
High concordance in plasma and CSF HIV-1 drug resistance mutations despite high cases of CSF viral escape in individuals with HIV-associated cryptococcal meningitis in Botswana.
Kelentse N, Moyo S, Choga WT, Lechiile K, Leeme TB, Lawrence DS, Kasvosve I, Musonda R, Mosepele M, Harrison TS, Jarvis JN, Gaseitsiwe S. Kelentse N, et al. Among authors: lawrence ds. J Antimicrob Chemother. 2022 Dec 23;78(1):180-184. doi: 10.1093/jac/dkac372. J Antimicrob Chemother. 2022. PMID: 36322466 Free PMC article. Clinical Trial.
Cost-effectiveness of single, high-dose, liposomal amphotericin regimen for HIV-associated cryptococcal meningitis in five countries in sub-Saharan Africa: an economic analysis of the AMBITION-cm trial.
Lawrence DS, Muthoga C, Meya DB, Tugume L, Williams D, Rajasingham R, Boulware DR, Mwandumba HC, Moyo M, Dziwani EN, Maheswaran H, Kanyama C, Hosseinipour MC, Chawinga C, Meintjes G, Schutz C, Comins K, Bango F, Muzoora C, Jjunju S, Nuwagira E, Mosepele M, Leeme T, Ndhlovu CE, Hlupeni A, Shamu S, Boyer-Chammard T, Molloy SF, Youssouf N, Chen T, Shiri T, Jaffar S, Harrison TS, Jarvis JN, Niessen LW; AMBITION Study Group. Lawrence DS, et al. Lancet Glob Health. 2022 Dec;10(12):e1845-e1854. doi: 10.1016/S2214-109X(22)00450-8. Lancet Glob Health. 2022. PMID: 36400090 Free PMC article.
Population pharmacokinetics and CSF penetration of flucytosine in adults with HIV-associated cryptococcal meningoencephalitis.
Stott KE, Ahmadu A, Kajanga C, Moyo M, Gondwe E, Chimang'anga W, Chasweka M, Unsworth J, Jimenez-Valverde A, Jagota B, Shah RV, Lawrence DS, Lalloo DG, Harrison T, Jarvis JN, Hope W, Mwandumba HC. Stott KE, et al. Among authors: lawrence ds. J Antimicrob Chemother. 2023 Apr 3;78(4):1015-1022. doi: 10.1093/jac/dkad038. J Antimicrob Chemother. 2023. PMID: 36857467 Free PMC article.
Reduction in mortality from HIV-related CNS infections in routine care in Africa (DREAMM): a before-and-after, implementation study.
Mfinanga S, Kanyama C, Kouanfack C, Nyirenda S, Kivuyo SL, Boyer-Chammard T, Phiri S, Ngoma J, Shimwela M, Nkungu D, Fomete LN, Simbauranga R, Chawinga C, Ngakam N, Heller T, Lontsi SS, Aghakishiyeva E, Jalava K, Fuller S, Reid AM, Rajasingham R, Lawrence DS, Hosseinipour MC, Beaumont E, Bradley J, Jaffar S, Lortholary O, Harrison T, Molloy SF, Sturny-Leclère A, Loyse A; DREAMM Consortium. Mfinanga S, et al. Among authors: lawrence ds. Lancet HIV. 2023 Oct;10(10):e663-e673. doi: 10.1016/S2352-3018(23)00182-0. Lancet HIV. 2023. PMID: 37802567 Free article.
Translating evidence into global impact: lessons for HIV research and policy development from the AMBITION trial.
Jarvis JN, Chou R, Harrison TS, Lawrence DS, Muthoga C, Mupeli K, Meya DB, Mwandumba HC, Kanyama C, Meintjes G, Leeme TB, Ndhlovu CE, Beattie P, Sued O, Pérez Casas C, Makanga M, Ford N. Jarvis JN, et al. Among authors: lawrence ds. Lancet Glob Health. 2023 Nov;11(11):e1688-e1690. doi: 10.1016/S2214-109X(23)00412-6. Lancet Glob Health. 2023. PMID: 37858577 Free PMC article. No abstract available.
204 results