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Expression of the membrane tetraspanin claudin 18 on cancer cells promotes T lymphocyte infiltration and antitumor immunity in pancreatic cancer.
De Sanctis F, Dusi S, Caligola S, Anselmi C, Petrova V, Rossi B, Angelini G, Erdeljan M, Wöll S, Schlitter AM, Metzler T, Steiger K, Borok Z, Bailey P, Bauer A, Halin C, Boschi F, Giugno R, Canè S, Lawlor R, Corbo V, Scarpa A, Constantin G, Ugel S, Vascotto F, Sahin U, Türeci Ö, Bronte V. De Sanctis F, et al. Among authors: lawlor r. Immunity. 2024 May 10:S1074-7613(24)00226-7. doi: 10.1016/j.immuni.2024.04.021. Online ahead of print. Immunity. 2024. PMID: 38749447 Free article.
Genetic Mapping and Phenotypic Analysis of GstE14 E.4.1 on Eye and Antennae Development in Drosophila melanogaster.
Thomson L, Shah HP, Akinwotu Adewale V, Beise A, Bliayang C, Cioch Z, Craig M, Crump A, Durdan M, Espinosa M, Feda K, Feist J, Fragoso A, Haro G, Hoffman B, Horne P, Houha N, Hounnou S, Inman A, Jakobsze D, Juarez-Morales Y, Khan Y, Kohler J, Lawlor R, Lieser B, Loitz R, Martinez E, Martinez A, Martinez M, Maza B, Mendoza B, Miller S, Mngodo H, O'Shea S, Piane SN, Raivala E, Ruger S, Singer A, Strand JE, Traylor A, Wright A, McCabe S, Pandit SS, Bieser K, Croonquist P, Taylor EE, Wittke-Thompson J, Kagey JD, Devergne O. Thomson L, et al. Among authors: lawlor r. MicroPubl Biol. 2024 Apr 13;2024:10.17912/micropub.biology.001019. doi: 10.17912/micropub.biology.001019. eCollection 2024. MicroPubl Biol. 2024. PMID: 38681673 Free PMC article.
Axon guidance cue SEMA3A promotes the aggressive phenotype of basal-like PDAC.
Lupo F, Pezzini F, Pasini D, Fiorini E, Adamo A, Veghini L, Bevere M, Frusteri C, Delfino P, D'agosto S, Andreani S, Piro G, Malinova A, Wang T, De Sanctis F, Lawlor RT, Hwang CI, Carbone C, Amelio I, Bailey P, Bronte V, Tuveson D, Scarpa A, Ugel S, Corbo V. Lupo F, et al. Among authors: lawlor rt. Gut. 2024 Apr 26:gutjnl-2023-329807. doi: 10.1136/gutjnl-2023-329807. Online ahead of print. Gut. 2024. PMID: 38670629 Free article.
A pleiotropy scan to discover new susceptibility loci for pancreatic ductal adenocarcinoma.
Giaccherini M, Rende M, Gentiluomo M, Corradi C, Archibugi L, Ermini S, Maiello E, Morelli L, van Eijck CHJ, Cavestro GM, Schneider M, Mickevicius A, Adamonis K, Basso D, Hlavac V, Gioffreda D, Talar-Wojnarowska R, Schöttker B, Lovecek M, Vanella G, Gazouli M, Uno M, Malecka-Wojciesko E, Vodicka P, Goetz M, Bijlsma MF, Petrone MC, Bazzocchi F, Kiudelis M, Szentesi A, Carrara S, Nappo G, Brenner H, Milanetto AC, Soucek P, Katzke V, Peduzzi G, Rizzato C, Pasquali C, Chen X, Capurso G, Hackert T, Bueno-de-Mesquita B, Uzunoglu FGG, Hegyi P, Greenhalf W, Theodoropoulos GEE, Sperti C, Perri F, Oliverius M, Mambrini A, Tavano F, Farinella R, Arcidiacono PG, Lucchesi M, Bunduc S, Kupcinskas J, Di Franco G, Stocker S, Neoptolemos JP, Bambi F, Jamroziak K, Testoni SGG, Aoki MN, Mohelnikova-Duchonova B, Izbicki JR, Pezzilli R, Lawlor RT, Kauffmann EF, López de Maturana E, Malats N, Canzian F, Campa D. Giaccherini M, et al. Among authors: lawlor rt. Mutagenesis. 2024 Apr 12:geae012. doi: 10.1093/mutage/geae012. Online ahead of print. Mutagenesis. 2024. PMID: 38606763
A Self-Assembled 3D Model Demonstrates How Stiffness Educates Tumor Cell Phenotypes and Therapy Resistance in Pancreatic Cancer.
Liu Y, Okesola BO, Osuna de la Peña D, Li W, Lin ML, Trabulo S, Tatari M, Lawlor RT, Scarpa A, Wang W, Knight M, Loessner D, Heeschen C, Mata A, Pearce OMT. Liu Y, et al. Among authors: lawlor rt. Adv Healthc Mater. 2024 Mar 12:e2301941. doi: 10.1002/adhm.202301941. Online ahead of print. Adv Healthc Mater. 2024. PMID: 38471128
A neuroligin-2-YAP axis regulates progression of pancreatic intraepithelial neoplasia.
Middonti E, Astanina E, Vallariello E, Hoza RM, Metovic J, Spadi R, Cristiano C, Papotti M, Allavena P, Novelli F, Parab S, Cappello P, Scarpa A, Lawlor R, Di Maio M, Arese M, Bussolino F. Middonti E, et al. Among authors: lawlor r. EMBO Rep. 2024 Apr;25(4):1886-1908. doi: 10.1038/s44319-024-00104-x. Epub 2024 Feb 27. EMBO Rep. 2024. PMID: 38413734 Free PMC article.
Polymorphisms in transcription factor binding sites and enhancer regions and pancreatic ductal adenocarcinoma risk.
Ünal P, Lu Y, Bueno-de-Mesquita B, van Eijck CHJ, Talar-Wojnarowska R, Szentesi A, Gazouli M, Kreivenaite E, Tavano F, Małecka-Wojciesko E, Erőss B, Oliverius M, Bunduc S, Nóbrega Aoki M, Vodickova L, Boggi U, Giaccherini M, Kondrackiene J, Chammas R, Palmieri O, Theodoropoulos GE, Bijlsma MF, Basso D, Mohelnikova-Duchonova B, Soucek P, Izbicki JR, Kiudelis V, Vanella G, Arcidiacono PG, Włodarczyk B, Hackert T, Schöttker B, Uzunoglu FG, Bambi F, Goetz M, Hlavac V, Brenner H, Perri F, Carrara S, Landi S, Hegyi P, Dijk F, Maiello E, Capretti G, Testoni SGG, Petrone MC, Stocker H, Ermini S, Archibugi L, Gentiluomo M, Cavestro GM, Pezzilli R, Di Franco G, Milanetto AC, Sperti C, Neoptolemos JP, Morelli L, Vokacova K, Pasquali C, Lawlor RT, Bazzocchi F, Kupcinskas J, Capurso G, Campa D, Canzian F. Ünal P, et al. Among authors: lawlor rt. Hum Genomics. 2024 Feb 2;18(1):12. doi: 10.1186/s40246-024-00576-x. Hum Genomics. 2024. PMID: 38308339 Free PMC article.
Pancreatic cancer acquires resistance to MAPK pathway inhibition by clonal expansion and adaptive DNA hypermethylation.
Godfrey LK, Forster J, Liffers ST, Schröder C, Köster J, Henschel L, Ludwig KU, Lähnemann D, Trajkovic-Arsic M, Behrens D, Scarpa A, Lawlor RT, Witzke KE, Sitek B, Johnsen SA, Rahmann S, Horsthemke B, Zeschnigk M, Siveke JT. Godfrey LK, et al. Among authors: lawlor rt. Clin Epigenetics. 2024 Jan 16;16(1):13. doi: 10.1186/s13148-024-01623-z. Clin Epigenetics. 2024. PMID: 38229153 Free PMC article.
Establishment and Thorough Characterization of Xenograft (PDX) Models Derived from Patients with Pancreatic Cancer for Molecular Analyses and Chemosensitivity Testing.
Behrens D, Pfohl U, Conrad T, Becker M, Brzezicha B, Büttner B, Wagner S, Hallas C, Lawlor R, Khazak V, Linnebacher M, Wartmann T, Fichtner I, Hoffmann J, Dahlmann M, Walther W. Behrens D, et al. Among authors: lawlor r. Cancers (Basel). 2023 Dec 8;15(24):5753. doi: 10.3390/cancers15245753. Cancers (Basel). 2023. PMID: 38136299 Free PMC article.
263 results