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Pharmacokinetic study of Tdp1 inhibitor resulted in a significant increase in antitumor effect in the treatment of Lewis lung carcinoma in mice by its combination with topotecan.
Okhina AA, Kornienko TE, Rogachev AD, Luzina OA, Popova NA, Nikolin VP, Zakharenko AL, Dyrkheeva NS, Pokrovsky AG, Salakhutdinov NF, Lavrik OI. Okhina AA, et al. Among authors: lavrik oi. J Pharm Biomed Anal. 2023 Nov 30;236:115731. doi: 10.1016/j.jpba.2023.115731. Epub 2023 Sep 18. J Pharm Biomed Anal. 2023. PMID: 37741072
PARP1 Gene Knockout Suppresses Expression of DNA Base Excision Repair Genes.
Zakharenko AL, Malakhova AA, Dyrkheeva NS, Okorokova LS, Medvedev SP, Zakian SM, Kabilov MR, Tupikin AA, Lavrik OI. Zakharenko AL, et al. Among authors: lavrik oi. Dokl Biochem Biophys. 2023 Feb;508(1):6-11. doi: 10.1134/S1607672922700028. Epub 2023 Jan 18. Dokl Biochem Biophys. 2023. PMID: 36653586 Free PMC article.
Transcriptomic analysis of HEK293A cells with a CRISPR/Cas9-mediated TDP1 knockout.
Dyrkheeva NS, Zakharenko AL, Malakhova AA, Okorokova LS, Shtokalo DN, Medvedev SP, Tupikin AA, Kabilov MR, Lavrik OI. Dyrkheeva NS, et al. Among authors: lavrik oi. Biochim Biophys Acta Gen Subj. 2024 Apr 14;1868(7):130616. doi: 10.1016/j.bbagen.2024.130616. Online ahead of print. Biochim Biophys Acta Gen Subj. 2024. PMID: 38621596
394 results