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An antibiotic from an uncultured bacterium binds to an immutable target.
Cell. 2023 Sep 14;186(19):4059-4073.e27. doi: 10.1016/j.cell.2023.07.038. Epub 2023 Aug 22.
Cell. 2023.
PMID: 37611581
Free article.
A new antibiotic from an uncultured bacterium binds to an immutable target.
Shukla R, Peoples AJ, Ludwig KC, Maity S, Derks MGN, de Benedetti S, Krueger AM, Vermeulen BJA, Lavore F, Honorato RV, Grein F, Bonvin A, Kubitscheck U, Breukink E, Achorn C, Nitti A, Schwalen CJ, Spoering AL, Ling LL, Hughes D, Lelli M, Roos WH, Lewis K, Schneider T, Weingarth M.
Shukla R, et al. Among authors: lavore f.
bioRxiv [Preprint]. 2023 May 15:2023.05.15.540765. doi: 10.1101/2023.05.15.540765.
bioRxiv. 2023.
PMID: 37292624
Free PMC article.
Updated.
Preprint.
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A combined fragment-based virtual screening and STD-NMR approach for the identification of E-cadherin ligands.
Vasile F, Lavore F, Gazzola S, Vettraino C, Parisini E, Piarulli U, Belvisi L, Civera M.
Vasile F, et al. Among authors: lavore f.
Front Chem. 2022 Aug 19;10:946087. doi: 10.3389/fchem.2022.946087. eCollection 2022.
Front Chem. 2022.
PMID: 36059878
Free PMC article.
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Teixobactin kills bacteria by a two-pronged attack on the cell envelope.
Shukla R, Lavore F, Maity S, Derks MGN, Jones CR, Vermeulen BJA, Melcrová A, Morris MA, Becker LM, Wang X, Kumar R, Medeiros-Silva J, van Beekveld RAM, Bonvin AMJJ, Lorent JH, Lelli M, Nowick JS, MacGillavry HD, Peoples AJ, Spoering AL, Ling LL, Hughes DE, Roos WH, Breukink E, Lewis K, Weingarth M.
Shukla R, et al. Among authors: lavore f.
Nature. 2022 Aug;608(7922):390-396. doi: 10.1038/s41586-022-05019-y. Epub 2022 Aug 3.
Nature. 2022.
PMID: 35922513
Free PMC article.
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Managing Experimental 3D Structures in the Beyond-Rule-of-5 Chemical Space: The Case of Rifampicin.
Ermondi G, Lavore F, Vallaro M, Tiana G, Vasile F, Caron G.
Ermondi G, et al. Among authors: lavore f.
Chemistry. 2021 Jul 16;27(40):10394-10404. doi: 10.1002/chem.202100961. Epub 2021 Jun 10.
Chemistry. 2021.
PMID: 34114271
Free PMC article.
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