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A clinically relevant large-scale biomanufacturing workflow to produce natural killer cells and natural killer cell-derived extracellular vesicles for cancer immunotherapy.
St-Denis-Bissonnette F, Cummings SE, Qiu S, Stalker A, Muradia G, Mehic J, Mediratta K, Kaczmarek S, Burger D, Lee SH, Wang L, Lavoie JR. St-Denis-Bissonnette F, et al. Among authors: lavoie jr. J Extracell Vesicles. 2023 Dec;12(12):e12387. doi: 10.1002/jev2.12387. J Extracell Vesicles. 2023. PMID: 38054534 Free PMC article.
Targeting CD73 with flavonoids inhibits cancer stem cells and increases lymphocyte infiltration in a triple-negative breast cancer mouse model.
Mediratta K, El-Sahli S, Marotel M, Awan MZ, Kirkby M, Salkini A, Kurdieh R, Abdisalam S, Shrestha A, Di Censo C, Sulaiman A, McGarry S, Lavoie JR, Liu Z, Lee SH, Li X, Sciumè G, D'Costa VM, Ardolino M, Wang L. Mediratta K, et al. Among authors: lavoie jr. Front Immunol. 2024 Mar 27;15:1366197. doi: 10.3389/fimmu.2024.1366197. eCollection 2024. Front Immunol. 2024. PMID: 38601156 Free PMC article.
Applications of Extracellular Vesicles in Triple-Negative Breast Cancer.
St-Denis-Bissonnette F, Khoury R, Mediratta K, El-Sahli S, Wang L, Lavoie JR. St-Denis-Bissonnette F, et al. Among authors: lavoie jr. Cancers (Basel). 2022 Jan 17;14(2):451. doi: 10.3390/cancers14020451. Cancers (Basel). 2022. PMID: 35053616 Free PMC article. Review.
Hollow-fiber bioreactor production of extracellular vesicles from human bone marrow mesenchymal stromal cells yields nanovesicles that mirrors the immuno-modulatory antigenic signature of the producer cell.
Gobin J, Muradia G, Mehic J, Westwood C, Couvrette L, Stalker A, Bigelow S, Luebbert CC, Bissonnette FS, Johnston MJW, Sauvé S, Tam RY, Wang L, Rosu-Myles M, Lavoie JR. Gobin J, et al. Among authors: lavoie jr. Stem Cell Res Ther. 2021 Feb 12;12(1):127. doi: 10.1186/s13287-021-02190-3. Stem Cell Res Ther. 2021. PMID: 33579358 Free PMC article.
Dysregulation of Ephrin receptor and PPAR signaling pathways in neural progenitor cells infected by Zika virus.
Thulasi Raman SN, Latreille E, Gao J, Zhang W, Wu J, Russell MS, Walrond L, Cyr T, Lavoie JR, Safronetz D, Cao J, Sauve S, Farnsworth A, Chen W, Shi PY, Wang Y, Wang L, Rosu-Myles M, Li X. Thulasi Raman SN, et al. Among authors: lavoie jr. Emerg Microbes Infect. 2020 Dec;9(1):2046-2060. doi: 10.1080/22221751.2020.1818631. Emerg Microbes Infect. 2020. PMID: 32873194 Free PMC article.
A comprehensive proteomics profiling identifies NRP1 as a novel identity marker of human bone marrow mesenchymal stromal cell-derived small extracellular vesicles.
Munshi A, Mehic J, Creskey M, Gobin J, Gao J, Rigg E, Muradia G, Luebbert CC, Westwood C, Stalker A, Allan DS, Johnston MJW, Cyr T, Rosu-Myles M, Lavoie JR. Munshi A, et al. Among authors: lavoie jr. Stem Cell Res Ther. 2019 Dec 18;10(1):401. doi: 10.1186/s13287-019-1516-2. Stem Cell Res Ther. 2019. PMID: 31852509 Free PMC article.
Unveiling Integrated Functional Pathways Leading to Enhanced Respiratory Disease Associated With Inactivated Respiratory Syncytial Viral Vaccine.
Russell MS, Creskey M, Muralidharan A, Li C, Gao J, Chen W, Larocque L, Lavoie JR, Farnsworth A, Rosu-Myles M, Hashem AM, Yauk CL, Cao J, Van Domselaar G, Cyr T, Li X. Russell MS, et al. Among authors: lavoie jr. Front Immunol. 2019 Mar 29;10:597. doi: 10.3389/fimmu.2019.00597. eCollection 2019. Front Immunol. 2019. PMID: 30984178 Free PMC article.
25 results