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Immunostimulatory nanoparticles go viral.
Huete-Carrasco J, Lavelle EC. Huete-Carrasco J, et al. Among authors: lavelle ec. Nat Mater. 2023 Mar;22(3):273-275. doi: 10.1038/s41563-023-01486-4. Nat Mater. 2023. PMID: 36864156 No abstract available.
Rational design of polymer-based particulate vaccine adjuvants.
Huete-Carrasco J, Lynch RI, Ward RW, Lavelle EC. Huete-Carrasco J, et al. Among authors: lavelle ec. Eur J Immunol. 2024 Feb;54(2):e2350512. doi: 10.1002/eji.202350512. Epub 2023 Dec 3. Eur J Immunol. 2024. PMID: 37994660 Review.
Mucosal vaccines - fortifying the frontiers.
Lavelle EC, Ward RW. Lavelle EC, et al. Nat Rev Immunol. 2022 Apr;22(4):236-250. doi: 10.1038/s41577-021-00583-2. Epub 2021 Jul 26. Nat Rev Immunol. 2022. PMID: 34312520 Free PMC article. Review.
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.
Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, Mullooly N, Mielke LA, Harris J, Coll RC, Mills KH, Mok KH, Newsholme P, Nuñez G, Yodoi J, Kahn SE, Lavelle EC, O'Neill LA. Masters SL, et al. Among authors: lavelle ec. Nat Immunol. 2010 Oct;11(10):897-904. doi: 10.1038/ni.1935. Epub 2010 Sep 12. Nat Immunol. 2010. PMID: 20835230 Free PMC article.
Hippo interferes with antiviral defences.
Muñoz-Wolf N, Lavelle EC. Muñoz-Wolf N, et al. Among authors: lavelle ec. Nat Cell Biol. 2017 Mar 31;19(4):267-269. doi: 10.1038/ncb3502. Nat Cell Biol. 2017. PMID: 28361938
Caspase-11 promotes allergic airway inflammation.
Zasłona Z, Flis E, Wilk MM, Carroll RG, Palsson-McDermott EM, Hughes MM, Diskin C, Banahan K, Ryan DG, Hooftman A, Misiak A, Kearney J, Lochnit G, Bertrams W, Greulich T, Schmeck B, McElvaney OJ, Mills KHG, Lavelle EC, Wygrecka M, Creagh EM, O'Neill LAJ. Zasłona Z, et al. Among authors: lavelle ec. Nat Commun. 2020 Feb 26;11(1):1055. doi: 10.1038/s41467-020-14945-2. Nat Commun. 2020. PMID: 32103022 Free PMC article.
Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages.
Dowling JK, Afzal R, Gearing LJ, Cervantes-Silva MP, Annett S, Davis GM, De Santi C, Assmann N, Dettmer K, Gough DJ, Bantug GR, Hamid FI, Nally FK, Duffy CP, Gorman AL, Liddicoat AM, Lavelle EC, Hess C, Oefner PJ, Finlay DK, Davey GP, Robson T, Curtis AM, Hertzog PJ, Williams BRG, McCoy CE. Dowling JK, et al. Among authors: lavelle ec. Nat Commun. 2021 Mar 5;12(1):1460. doi: 10.1038/s41467-021-21617-2. Nat Commun. 2021. PMID: 33674584 Free PMC article.
133 results