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Astrocytes modulate neurodegenerative phenotypes associated with glaucoma in OPTN(E50K) human stem cell-derived retinal ganglion cells.
Stem Cell Reports. 2022 Jul 12;17(7):1636-1649. doi: 10.1016/j.stemcr.2022.05.006. Epub 2022 Jun 16.
Stem Cell Reports. 2022.
PMID: 35714595
Free PMC article.
Retinal Ganglion Cells With a Glaucoma OPTN(E50K) Mutation Exhibit Neurodegenerative Phenotypes when Derived from Three-Dimensional Retinal Organoids.
VanderWall KB, Huang KC, Pan Y, Lavekar SS, Fligor CM, Allsop AR, Lentsch KA, Dang P, Zhang C, Tseng HC, Cummins TR, Meyer JS.
VanderWall KB, et al. Among authors: lavekar ss.
Stem Cell Reports. 2020 Jul 14;15(1):52-66. doi: 10.1016/j.stemcr.2020.05.009. Epub 2020 Jun 11.
Stem Cell Reports. 2020.
PMID: 32531194
Free PMC article.
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Differentiation of retinal organoids from human pluripotent stem cells.
Fligor CM, Huang KC, Lavekar SS, VanderWall KB, Meyer JS.
Fligor CM, et al. Among authors: lavekar ss.
Methods Cell Biol. 2020;159:279-302. doi: 10.1016/bs.mcb.2020.02.005. Epub 2020 Mar 11.
Methods Cell Biol. 2020.
PMID: 32586447
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Extension of retinofugal projections in an assembled model of human pluripotent stem cell-derived organoids.
Fligor CM, Lavekar SS, Harkin J, Shields PK, VanderWall KB, Huang KC, Gomes C, Meyer JS.
Fligor CM, et al. Among authors: lavekar ss.
Stem Cell Reports. 2021 Sep 14;16(9):2228-2241. doi: 10.1016/j.stemcr.2021.05.009. Epub 2021 Jun 10.
Stem Cell Reports. 2021.
PMID: 34115986
Free PMC article.
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Asteroid impact: the potential of astrocytes to modulate human neural networks within organoids.
Lavekar SS, Patel MD, Montalvo-Parra MD, Krencik R.
Lavekar SS, et al.
Front Neurosci. 2023 Nov 22;17:1305921. doi: 10.3389/fnins.2023.1305921. eCollection 2023.
Front Neurosci. 2023.
PMID: 38075269
Free PMC article.
Review.
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Development of a three-dimensional organoid model to explore early retinal phenotypes associated with Alzheimer's disease.
Lavekar SS, Harkin J, Hernandez M, Gomes C, Patil S, Huang KC, Puntambekar SS, Lamb BT, Meyer JS.
Lavekar SS, et al.
Sci Rep. 2023 Aug 24;13(1):13827. doi: 10.1038/s41598-023-40382-4.
Sci Rep. 2023.
PMID: 37620502
Free PMC article.
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Autophagy disruption reduces mTORC1 activation leading to retinal ganglion cell neurodegeneration associated with glaucoma.
Huang KC, Gomes C, Shiga Y, Belforte N, VanderWall KB, Lavekar SS, Fligor CM, Harkin J, Di Polo A, Meyer JS.
Huang KC, et al. Among authors: lavekar ss.
bioRxiv [Preprint]. 2023 Jan 4:2023.01.04.522687. doi: 10.1101/2023.01.04.522687.
bioRxiv. 2023.
PMID: 36711831
Free PMC article.
Preprint.
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