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CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration.
Combadière C, Feumi C, Raoul W, Keller N, Rodéro M, Pézard A, Lavalette S, Houssier M, Jonet L, Picard E, Debré P, Sirinyan M, Deterre P, Ferroukhi T, Cohen SY, Chauvaud D, Jeanny JC, Chemtob S, Behar-Cohen F, Sennlaub F. Combadière C, et al. Among authors: lavalette s. J Clin Invest. 2007 Oct;117(10):2920-8. doi: 10.1172/JCI31692. J Clin Invest. 2007. PMID: 17909628 Free PMC article.
CD36 deficiency leads to choroidal involution via COX2 down-regulation in rodents.
Houssier M, Raoul W, Lavalette S, Keller N, Guillonneau X, Baragatti B, Jonet L, Jeanny JC, Behar-Cohen F, Coceani F, Scherman D, Lachapelle P, Ong H, Chemtob S, Sennlaub F. Houssier M, et al. Among authors: lavalette s. PLoS Med. 2008 Feb;5(2):e39. doi: 10.1371/journal.pmed.0050039. PLoS Med. 2008. PMID: 18288886 Free PMC article.
Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B.
Lejmi E, Leconte L, Pédron-Mazoyer S, Ropert S, Raoul W, Lavalette S, Bouras I, Feron JG, Maitre-Boube M, Assayag F, Feumi C, Alemany M, Jie TX, Merkulova T, Poupon MF, Ruchoux MM, Tobelem G, Sennlaub F, Plouët J. Lejmi E, et al. Among authors: lavalette s. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12491-6. doi: 10.1073/pnas.0804008105. Epub 2008 Aug 21. Proc Natl Acad Sci U S A. 2008. PMID: 18719102 Free PMC article.
MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo.
Raoul W, Poupel L, Tregouet DA, Lavalette S, Camelo S, Keller N, Krumeich S, Calippe B, Guillonneau X, Behar-Cohen F, Cohen SY, Baatz H, Combadière C, Théry C, Sennlaub F. Raoul W, et al. Among authors: lavalette s. PLoS One. 2012;7(3):e33244. doi: 10.1371/journal.pone.0033244. Epub 2012 Mar 15. PLoS One. 2012. PMID: 22438901 Free PMC article.
Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages.
Camelo S, Raoul W, Lavalette S, Calippe B, Cristofaro B, Levy O, Houssier M, Sulpice E, Jonet L, Klein C, Devevre E, Thuret G, Duarte A, Eichmann A, Leconte L, Guillonneau X, Sennlaub F. Camelo S, et al. Among authors: lavalette s. Angiogenesis. 2012 Dec;15(4):609-22. doi: 10.1007/s10456-012-9290-0. Epub 2012 Aug 7. Angiogenesis. 2012. PMID: 22869002 Free PMC article.
CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice.
Sennlaub F, Auvynet C, Calippe B, Lavalette S, Poupel L, Hu SJ, Dominguez E, Camelo S, Levy O, Guyon E, Saederup N, Charo IF, Rooijen NV, Nandrot E, Bourges JL, Behar-Cohen F, Sahel JA, Guillonneau X, Raoul W, Combadiere C. Sennlaub F, et al. Among authors: lavalette s. EMBO Mol Med. 2013 Nov;5(11):1775-93. doi: 10.1002/emmm.201302692. Epub 2013 Oct 21. EMBO Mol Med. 2013. PMID: 24142887 Free PMC article.
18 results