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A cell atlas of human thymic development defines T cell repertoire formation.
Park JE, Botting RA, Domínguez Conde C, Popescu DM, Lavaert M, Kunz DJ, Goh I, Stephenson E, Ragazzini R, Tuck E, Wilbrey-Clark A, Roberts K, Kedlian VR, Ferdinand JR, He X, Webb S, Maunder D, Vandamme N, Mahbubani KT, Polanski K, Mamanova L, Bolt L, Crossland D, de Rita F, Fuller A, Filby A, Reynolds G, Dixon D, Saeb-Parsy K, Lisgo S, Henderson D, Vento-Tormo R, Bayraktar OA, Barker RA, Meyer KB, Saeys Y, Bonfanti P, Behjati S, Clatworthy MR, Taghon T, Haniffa M, Teichmann SA. Park JE, et al. Among authors: lavaert m. Science. 2020 Feb 21;367(6480):eaay3224. doi: 10.1126/science.aay3224. Science. 2020. PMID: 32079746 Free PMC article.
Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes.
Lavaert M, Liang KL, Vandamme N, Park JE, Roels J, Kowalczyk MS, Li B, Ashenberg O, Tabaka M, Dionne D, Tickle TL, Slyper M, Rozenblatt-Rosen O, Vandekerckhove B, Leclercq G, Regev A, Van Vlierberghe P, Guilliams M, Teichmann SA, Saeys Y, Taghon T. Lavaert M, et al. Immunity. 2020 Jun 16;52(6):1088-1104.e6. doi: 10.1016/j.immuni.2020.03.019. Epub 2020 Apr 17. Immunity. 2020. PMID: 32304633 Free article.
Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development.
Dolens AC, Durinck K, Lavaert M, Van der Meulen J, Velghe I, De Medts J, Weening K, Roels J, De Mulder K, Volders PJ, De Preter K, Kerre T, Vandekerckhove B, Leclercq G, Vandesompele J, Mestdagh P, Van Vlierberghe P, Speleman F, Taghon T. Dolens AC, et al. Among authors: lavaert m. EMBO Rep. 2020 May 6;21(5):e49006. doi: 10.15252/embr.201949006. Epub 2020 Apr 7. EMBO Rep. 2020. PMID: 32255245 Free PMC article.
T cell development made EZ.
Lavaert M, Bhandoola A. Lavaert M, et al. Cell Stem Cell. 2022 Aug 4;29(8):1155-1156. doi: 10.1016/j.stem.2022.07.003. Cell Stem Cell. 2022. PMID: 35931025 Free article.
Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut.
Das A, Martinez-Ruiz GU, Bouladoux N, Stacy A, Moraly J, Vega-Sendino M, Zhao Y, Lavaert M, Ding Y, Morales-Sanchez A, Harly C, Seedhom MO, Chari R, Awasthi P, Ikeuchi T, Wang Y, Zhu J, Moutsopoulos NM, Chen W, Yewdell JW, Shapiro VS, Ruiz S, Taylor N, Belkaid Y, Bhandoola A. Das A, et al. Among authors: lavaert m. Immunity. 2024 Apr 18:S1074-7613(24)00206-1. doi: 10.1016/j.immuni.2024.04.001. Online ahead of print. Immunity. 2024. PMID: 38677292
Bone marrow plasma cells require P2RX4 to sense extracellular ATP.
Ishikawa M, Hasanali ZS, Zhao Y, Das A, Lavaert M, Roman CJ, Londregan J, Allman D, Bhandoola A. Ishikawa M, et al. Among authors: lavaert m. Nature. 2024 Feb;626(8001):1102-1107. doi: 10.1038/s41586-024-07047-2. Epub 2024 Feb 14. Nature. 2024. PMID: 38355795 Free PMC article.
15 results