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Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages.
He W, Henne A, Lauterbach M, Geißmar E, Nikolka F, Kho C, Heinz A, Dostert C, Grusdat M, Cordes T, Härm J, Goldmann O, Ewen A, Verschueren C, Blay-Cadanet J, Geffers R, Garritsen H, Kneiling M, Holm CK, Metallo CM, Medina E, Abdullah Z, Latz E, Brenner D, Hiller K. He W, et al. Among authors: lauterbach m. Nat Metab. 2022 May;4(5):524-533. doi: 10.1038/s42255-022-00565-1. Epub 2022 Jun 2. Nat Metab. 2022. PMID: 35655024 Free PMC article.
Macrophage inflammatory state in Type 1 diabetes: triggered by NLRP3/iNOS pathway and attenuated by docosahexaenoic acid.
Davanso MR, Crisma AR, Braga TT, Masi LN, do Amaral CL, Leal VNC, de Lima DS, Patente TA, Barbuto JA, Corrêa-Giannella ML, Lauterbach M, Kolbe CC, Latz E, Camara NOS, Pontillo A, Curi R. Davanso MR, et al. Among authors: lauterbach m. Clin Sci (Lond). 2021 Jan 15;135(1):19-34. doi: 10.1042/CS20201348. Clin Sci (Lond). 2021. PMID: 33399849
Sensing soluble uric acid by Naip1-Nlrp3 platform.
Braga TT, Davanso MR, Mendes D, de Souza TA, de Brito AF, Cruz MC, Hiyane MI, de Lima DS, Nunes V, de Fátima Giarola J, Souto DEP, Próchnicki T, Lauterbach M, Biscaia SMP, de Freitas RA, Curi R, Pontillo A, Latz E, Camara NOS. Braga TT, et al. Among authors: lauterbach m. Cell Death Dis. 2021 Feb 5;12(2):158. doi: 10.1038/s41419-021-03445-w. Cell Death Dis. 2021. PMID: 33547278 Free PMC article.
ATP-binding and hydrolysis of human NLRP3.
Brinkschulte R, Fußhöller DM, Hoss F, Rodríguez-Alcázar JF, Lauterbach MA, Kolbe CC, Rauen M, Ince S, Herrmann C, Latz E, Geyer M. Brinkschulte R, et al. Among authors: lauterbach ma. Commun Biol. 2022 Nov 3;5(1):1176. doi: 10.1038/s42003-022-04120-2. Commun Biol. 2022. PMID: 36329210 Free PMC article.
152 results