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Wnt/β-catenin and NFκB signaling synergize to trigger growth factor-free regeneration of adult primary human hepatocytes.
Oliva-Vilarnau N, Beusch CM, Sabatier P, Sakaraki E, Tjaden A, Graetz L, Büttner FA, Dorotea D, Nguyen M, Bergqvist F, Sundström Y, Müller S, Zubarev RA, Schulte G, Tredup C, Gramignoli R, Tietge UJF, Lauschke VM. Oliva-Vilarnau N, et al. Among authors: lauschke vm. Hepatology. 2023 Oct 23. doi: 10.1097/HEP.0000000000000648. Online ahead of print. Hepatology. 2023. PMID: 37870288
Calcium Signaling in Liver Injury and Regeneration.
Oliva-Vilarnau N, Hankeova S, Vorrink SU, Mkrtchian S, Andersson ER, Lauschke VM. Oliva-Vilarnau N, et al. Among authors: lauschke vm. Front Med (Lausanne). 2018 Jul 4;5:192. doi: 10.3389/fmed.2018.00192. eCollection 2018. Front Med (Lausanne). 2018. PMID: 30023358 Free PMC article. Review.
Bioengineered Pancreas-Liver Crosstalk in a Microfluidic Coculture Chip Identifies Human Metabolic Response Signatures in Prediabetic Hyperglycemia.
Zandi Shafagh R, Youhanna S, Keulen J, Shen JX, Taebnia N, Preiss LC, Klein K, Büttner FA, Bergqvist M, van der Wijngaart W, Lauschke VM. Zandi Shafagh R, et al. Among authors: lauschke vm. Adv Sci (Weinh). 2022 Dec;9(34):e2203368. doi: 10.1002/advs.202203368. Epub 2022 Oct 26. Adv Sci (Weinh). 2022. PMID: 36285680 Free PMC article.
Deep Annotation of Donated Chemical Probes (DCP) in Organotypic Human Liver Cultures and Patient-Derived Organoids from Tumor and Normal Colorectum.
Tredup C, Ndreshkjana B, Schneider NS, Tjaden A, Kemas AM, Youhanna S, Lauschke VM, Berger BT, Krämer A, Berger LM, Röhm S, Knapp S, Farin HF, Müller S. Tredup C, et al. Among authors: lauschke vm. ACS Chem Biol. 2023 Apr 21;18(4):822-836. doi: 10.1021/acschembio.2c00877. Epub 2023 Mar 21. ACS Chem Biol. 2023. PMID: 36944371 Free PMC article.
Comparative analysis of YAP/TEAD inhibitors in 2D and 3D cultures of primary human hepatocytes reveals a novel non-canonical mechanism of CYP induction.
Oliva-Vilarnau N, Vorrink SU, Büttner FA, Heinrich T, Sensbach J, Koscielski I, Wienke D, Petersson C, Perrin D, Lauschke VM. Oliva-Vilarnau N, et al. Among authors: lauschke vm. Biochem Pharmacol. 2023 Sep;215:115755. doi: 10.1016/j.bcp.2023.115755. Epub 2023 Aug 20. Biochem Pharmacol. 2023. PMID: 37607620 Free article.
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics.
Wright SC, Motso A, Koutsilieri S, Beusch CM, Sabatier P, Berghella A, Blondel-Tepaz É, Mangenot K, Pittarokoilis I, Sismanoglou DC, Le Gouill C, Olsen JV, Zubarev RA, Lambert NA, Hauser AS, Bouvier M, Lauschke VM. Wright SC, et al. Among authors: lauschke vm. Nat Commun. 2023 Oct 9;14(1):6243. doi: 10.1038/s41467-023-41893-4. Nat Commun. 2023. PMID: 37813859 Free PMC article.
171 results