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GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics.
Wright SC, Motso A, Koutsilieri S, Beusch CM, Sabatier P, Berghella A, Blondel-Tepaz É, Mangenot K, Pittarokoilis I, Sismanoglou DC, Le Gouill C, Olsen JV, Zubarev RA, Lambert NA, Hauser AS, Bouvier M, Lauschke VM. Wright SC, et al. Among authors: lauschke vm. Nat Commun. 2023 Oct 9;14(1):6243. doi: 10.1038/s41467-023-41893-4. Nat Commun. 2023. PMID: 37813859 Free PMC article.
Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation.
Novak M, Vajrychova M, Koutsilieri S, Sismanoglou DC, Kobrlova T, Prchal L, Svobodova B, Korabecny J, Zarybnicky T, Raisova-Stuchlikova L, Skalova L, Lauschke VM, Kučera R, Soukup O. Novak M, et al. Among authors: lauschke vm. ACS Chem Biol. 2023 Sep 15;18(9):1993-2002. doi: 10.1021/acschembio.3c00219. Epub 2023 Aug 25. ACS Chem Biol. 2023. PMID: 37622522
Wnt/β-catenin and NFκB signaling synergize to trigger growth factor-free regeneration of adult primary human hepatocytes.
Oliva-Vilarnau N, Beusch CM, Sabatier P, Sakaraki E, Tjaden A, Graetz L, Büttner FA, Dorotea D, Nguyen M, Bergqvist F, Sundström Y, Müller S, Zubarev RA, Schulte G, Tredup C, Gramignoli R, Tietge UJF, Lauschke VM. Oliva-Vilarnau N, et al. Among authors: lauschke vm. Hepatology. 2024 Jun 1;79(6):1337-1351. doi: 10.1097/HEP.0000000000000648. Epub 2023 Oct 23. Hepatology. 2024. PMID: 37870288 Free PMC article.
Crimean-Congo haemorrhagic fever virus uses LDLR to bind and enter host cells.
Monteil VM, Wright SC, Dyczynski M, Kellner MJ, Appelberg S, Platzer SW, Ibrahim A, Kwon H, Pittarokoilis I, Mirandola M, Michlits G, Devignot S, Elder E, Abdurahman S, Bereczky S, Bagci B, Youhanna S, Aastrup T, Lauschke VM, Salata C, Elaldi N, Weber F, Monserrat N, Hawman DW, Feldmann H, Horn M, Penninger JM, Mirazimi A. Monteil VM, et al. Among authors: lauschke vm. Nat Microbiol. 2024 Mar 28. doi: 10.1038/s41564-024-01672-3. Online ahead of print. Nat Microbiol. 2024. PMID: 38548922
171 results