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Antidepressant drugs act by directly binding to TRKB neurotrophin receptors.
Casarotto PC, Girych M, Fred SM, Kovaleva V, Moliner R, Enkavi G, Biojone C, Cannarozzo C, Sahu MP, Kaurinkoski K, Brunello CA, Steinzeig A, Winkel F, Patil S, Vestring S, Serchov T, Diniz CRAF, Laukkanen L, Cardon I, Antila H, Rog T, Piepponen TP, Bramham CR, Normann C, Lauri SE, Saarma M, Vattulainen I, Castrén E. Casarotto PC, et al. Among authors: lauri se. Cell. 2021 Mar 4;184(5):1299-1313.e19. doi: 10.1016/j.cell.2021.01.034. Epub 2021 Feb 18. Cell. 2021. PMID: 33606976 Free PMC article.
Microtechnologies to fuel neurobiological research with nanometer precision.
Brunello CA, Jokinen V, Sakha P, Terazono H, Nomura F, Kaneko T, Lauri SE, Franssila S, Rivera C, Yasuda K, Huttunen HJ. Brunello CA, et al. Among authors: lauri se. J Nanobiotechnology. 2013 Apr 10;11:11. doi: 10.1186/1477-3155-11-11. J Nanobiotechnology. 2013. PMID: 23575365 Free PMC article. Review.
Isoflurane produces antidepressant effects and induces TrkB signaling in rodents.
Antila H, Ryazantseva M, Popova D, Sipilä P, Guirado R, Kohtala S, Yalcin I, Lindholm J, Vesa L, Sato V, Cordeira J, Autio H, Kislin M, Rios M, Joca S, Casarotto P, Khiroug L, Lauri S, Taira T, Castrén E, Rantamäki T. Antila H, et al. Sci Rep. 2017 Aug 10;7(1):7811. doi: 10.1038/s41598-017-08166-9. Sci Rep. 2017. PMID: 28798343 Free PMC article.
Kainate Receptor Auxiliary Subunit NETO2-Related Cued Fear Conditioning Impairments Associate with Defects in Amygdala Development and Excitability.
Mennesson M, Orav E, Gigliotta A, Kulesskaya N, Saarnio S, Kirjavainen A, Kesaf S, Winkel F, Llach Pou M, Umemori J, Voikar V, Risbrough V, Partanen J, Castrén E, Lauri SE, Hovatta I. Mennesson M, et al. Among authors: lauri se. eNeuro. 2020 Aug 27;7(4):ENEURO.0541-19.2020. doi: 10.1523/ENEURO.0541-19.2020. Print 2020 Jul/Aug. eNeuro. 2020. PMID: 32788298 Free PMC article.
Pharmacological and optical activation of TrkB in Parvalbumin interneurons regulate intrinsic states to orchestrate cortical plasticity.
Winkel F, Ryazantseva M, Voigt MB, Didio G, Lilja A, Llach Pou M, Steinzeig A, Harkki J, Englund J, Khirug S, Rivera C, Palva S, Taira T, Lauri SE, Umemori J, Castrén E. Winkel F, et al. Among authors: lauri se. Mol Psychiatry. 2021 Dec;26(12):7247-7256. doi: 10.1038/s41380-021-01211-0. Epub 2021 Jul 28. Mol Psychiatry. 2021. PMID: 34321594 Free PMC article.
Activation of TrkB in Parvalbumin interneurons is required for the promotion of reversal learning in spatial and fear memory by antidepressants.
Jetsonen E, Didio G, Winkel F, Llach Pou M, Boj C, Kuczynski-Noyau L, Võikar V, Guirado R, Taira T, Lauri SE, Castrén E, Umemori J. Jetsonen E, et al. Among authors: lauri se. Neuropsychopharmacology. 2023 Jun;48(7):1021-1030. doi: 10.1038/s41386-023-01562-y. Epub 2023 Mar 21. Neuropsychopharmacology. 2023. PMID: 36944718 Free PMC article.
KCC2 interacts with the dendritic cytoskeleton to promote spine development.
Li H, Khirug S, Cai C, Ludwig A, Blaesse P, Kolikova J, Afzalov R, Coleman SK, Lauri S, Airaksinen MS, Keinänen K, Khiroug L, Saarma M, Kaila K, Rivera C. Li H, et al. Neuron. 2007 Dec 20;56(6):1019-33. doi: 10.1016/j.neuron.2007.10.039. Neuron. 2007. PMID: 18093524 Free article.
Kainate receptors in the developing neuronal networks.
Lauri SE, Ryazantseva M, Orav E, Vesikansa A, Taira T. Lauri SE, et al. Neuropharmacology. 2021 Sep 1;195:108585. doi: 10.1016/j.neuropharm.2021.108585. Epub 2021 Apr 25. Neuropharmacology. 2021. PMID: 33910033 Free article. Review.
65 results